INTERNAL ADAN INFORMATION

• Record: 260
• Number: 145
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: CD3Z_HUMAN by SMART
• Basic UniProtKB Entry: CD3Z_HUMAN
• InterPro link: CD3Z_HUMAN
• Swiss-Prot ENTRY: CD3Z_HUMAN
• Swiss-Prot AC number: P20963
• Sequence: P20963
• Pfam database: CD3Z_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P20963
• BLAST for whole protein: P20963
• SAS for whole protein: P20963
• BLAST for modular domain: 1TCE
• SAS for domain: 1TCE

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1TCE2_mat 
• iPfam: SH2
• PsiBase: 1TCE
• MINT: whole protein: P20963 or domain: 1TCE
• DOMINO database: P20963
• APID: P20963

• Title: SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE
• Experimental Technique: NMR, MINIMIZED AVERAGE STRUCTURE
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Zhou et al. 1995 Proc.Natl.Acad.Sci.U.S.A. 92, 7784
• Sequence domain: seqA_1tce2.txt
• Peptide sequence of ligand: GHDGLXQGLSTATK
• Biochemical affinity data for: 1tce
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1TCE
• RCSB_PDB_ID: 1TCE
• SMART: SH2
• PDBsum (domain): 1TCE
• PDBsum (Ligand): 1TCE
• MSD (summary): 1TCE
• MSD (ligands): 1TCE
• Molecular Surface: 1tce

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.