INTERNAL ADAN INFORMATION

• Record: 248
• Number: 133
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: P85A_HUMAN by SMART
• Basic UniProtKB Entry: P85A_HUMAN
• InterPro link: P85A_HUMAN
• Swiss-Prot ENTRY: P85A_HUMAN
• Swiss-Prot AC number: P27986
• Sequence: P27986
• Pfam database: P85A_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P27986
• BLAST for whole protein: P27986
• SAS for whole protein: P27986
• BLAST for modular domain: 1PIC
• SAS for domain: 1PIC

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1PIC2_mat 
• iPfam: SH2
• PsiBase: 1PIC
• MINT: whole protein: P27986 or domain: 1PIC
• DOMINO database: P27986
• APID: P27986

• Title: PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, NMR, MINIMIZED MEAN STRUCTURE
• Experimental Technique: NMR, MINIMIZED MEAN STRUCTURE
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Breeze et al. 1996 EMBO J. 15, 3579
• Sequence domain: seqA_1pic2.txt
• Peptide sequence of ligand: XXVPML
• Biochemical affinity data for: 1pic
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1PIC
• RCSB_PDB_ID: 1PIC
• SMART: SH2
• PDBsum (domain): 1PIC
• PDBsum (Ligand): 1PIC
• MSD (summary): 1PIC
• MSD (ligands): 1PIC
• Molecular Surface: 1pic

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.