INTERNAL ADAN INFORMATION

• Record: 216
• Number: 101
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: GRBA_HUMAN by SMART
• Basic UniProtKB Entry: GRBA_HUMAN
• InterPro link: GRBA_HUMAN
• Swiss-Prot ENTRY: GRBA_HUMAN
• Swiss-Prot AC number: Q13322
• Sequence: Q13322
• Pfam database: GRBA_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q13322
• BLAST for whole protein: Q13322
• SAS for whole protein: Q13322
• BLAST for modular domain: 1NRV
• SAS for domain: 1NRV

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 1NRV
• MINT: whole protein: Q13322 or domain: 1NRV
• DOMINO database: Q13322
• APID: Q13322

• Title: CRYSTAL STRUCTURE OF THE SH2 DOMAIN OF GRB10
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.65
• Protein Source: Homo sapiens
• Reference: Stein et al. 2003 J.Biol.Chem. 278, 13257
• Sequence domain: seqA_1nrv2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1nrv
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1NRV
• RCSB_PDB_ID: 1NRV
• SMART: SH2
• PDBsum (domain): 1NRV
• PDBsum (Ligand): 1NRV
• MSD (summary): 1NRV
• MSD (ligands): 1NRV
• Molecular Surface: 1nrv

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.