INTERNAL ADAN INFORMATION

• Record: 204
• Number: 89
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: SRC_RSVSR by SMART
• Basic UniProtKB Entry: SRC_RSVSR
• InterPro link: SRC_RSVSR
• Swiss-Prot ENTRY: SRC_RSVSR
• Swiss-Prot AC number: P00524
• Sequence: P00524
• Pfam database: SRC_RSVSR

ALIGNMENT

• BLAST against Swiss-Prot: P00524
• BLAST for whole protein: P00524
• SAS for whole protein: P00524
• BLAST for modular domain: 1KC2
• SAS for domain: 1KC2

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1KC22_mat 
• iPfam: SH2
• PsiBase: 1KC2
• MINT: whole protein: P00524 or domain: 1KC2
• DOMINO database: P00524
• APID: P00524

• Title: STRUCTURE OF THE TRIPLE (LYS(BETA)D3ALA, ASP(BETA)C8ALA, ASPCD2ALA) MUTANT OF THE SRC SH2 DOMAIN BOUND TO THE PQPYEEIPI PEPTIDE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.1
• Protein Source: Rous sarcoma virus
• Reference: Lubman and Waksman 2002 J.Mol.Biol. 316, 291
• Sequence domain: seqA_1kc22.txt
• Peptide sequence of ligand: PQXEEIPI
• Biochemical affinity data for: 1kc2
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1KC2
• RCSB_PDB_ID: 1KC2
• SMART: SH2
• PDBsum (domain): 1KC2
• PDBsum (Ligand): 1KC2
• MSD (summary): 1KC2
• MSD (ligands): 1KC2
• Molecular Surface: 1kc2

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.