INTERNAL ADAN INFORMATION

• Record: 202
• Number: 87
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: SH2A_HUMAN by SMART
• Basic UniProtKB Entry: SH2A_HUMAN
• InterPro link: SH2A_HUMAN
• Swiss-Prot ENTRY: SH2A_HUMAN
• Swiss-Prot AC number: Q9NP31
• Sequence: Q9NP31
• Pfam database: SH2A_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q9NP31
• BLAST for whole protein: Q9NP31
• SAS for whole protein: Q9NP31
• BLAST for modular domain: 1KA6
• SAS for domain: 1KA6

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1KA62_mat 
• iPfam: SH2
• PsiBase: 1KA6
• MINT: whole protein: Q9NP31 or domain: 1KA6
• DOMINO database: Q9NP31
• APID: Q9NP31

• Title: SAP/SH2D1A BOUND TO PEPTIDE N-PY
• Experimental Technique: NMR, MINIMIZED AVERAGE STRUCTURE
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Hwang et al. 2002 EMBO J. 21, 314
• Sequence domain: seqA_1ka62.txt
• Peptide sequence of ligand: RKSLTIXAX
• Biochemical affinity data for: 1ka6
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1KA6
• RCSB_PDB_ID: 1KA6
• SMART: SH2
• PDBsum (domain): 1KA6
• PDBsum (Ligand): 1KA6
• MSD (summary): 1KA6
• MSD (ligands): 1KA6
• Molecular Surface: 1ka6

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.