INTERNAL ADAN INFORMATION

• Record: 175
• Number: 47
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: LCK_HUMAN by SMART
• Basic UniProtKB Entry: LCK_HUMAN
• InterPro link: LCK_HUMAN
• Swiss-Prot ENTRY: LCK_HUMAN
• Swiss-Prot AC number: P06239
• Sequence: P06239
• Pfam database: LCK_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P06239
• BLAST for whole protein: P06239
• SAS for whole protein: P06239
• BLAST for modular domain: 1CWE
• SAS for domain: 1CWE

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1CWE2_mat 
• iPfam: SH2
• PsiBase: 1CWE
• MINT: whole protein: P06239 or domain: 1CWE
• DOMINO database: P06239
• APID: P06239

• Title: HUMAN P56LCK TYROSINE KINASE COMPLEXED WITH PHOSPHONOPEPTIDE
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.3
• Protein Source: Homo sapiens
• Reference: Mikol et al. 1995 J.Mol.Biol. 246, 344
• Sequence domain: seqA_1cwe2.txt
• Peptide sequence of ligand: XQFEEIP
• Biochemical affinity data for: 1cwe
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1CWE
• RCSB_PDB_ID: 1CWE
• SMART: SH2
• PDBsum (domain): 1CWE
• PDBsum (Ligand): 1CWE
• MSD (summary): 1CWE
• MSD (ligands): 1CWE
• Molecular Surface: 1cwe

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.