INTERNAL ADAN INFORMATION

• Record: 172
• Number: 44
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: KSYK_HUMAN by SMART
• Basic UniProtKB Entry: KSYK_HUMAN
• InterPro link: KSYK_HUMAN
• Swiss-Prot ENTRY: KSYK_HUMAN
• Swiss-Prot AC number: P43405
• Sequence: P43405
• Pfam database: KSYK_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P43405
• BLAST for whole protein: P43405
• SAS for whole protein: P43405
• BLAST for modular domain: 1CSY
• SAS for domain: 1CSY

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1CSY2_mat 
• iPfam: SH2
• PsiBase: 1CSY
• MINT: whole protein: P43405 or domain: 1CSY
• DOMINO database: P43405
• APID: P43405

• Title: SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR
• Experimental Technique: NMR, 20 STRUCTURES
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Narula et al. 1995 Structure 3, 1061
• Sequence domain: seqA_1csy2.txt
• Peptide sequence of ligand: XTXETLX
• Biochemical affinity data for: 1csy
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1CSY
• RCSB_PDB_ID: 1CSY
• SMART: SH2
• PDBsum (domain): 1CSY
• PDBsum (Ligand): 1CSY
• MSD (summary): 1CSY
• MSD (ligands): 1CSY
• Molecular Surface: 1csy

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.