INTERNAL ADAN INFORMATION

• Record: 1630
• Number: 169
• Inclusion date: 4-IX-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P85A_HUMAN by SMART
• Basic UniProtKB Entry: P85A_HUMAN
• InterPro link: P85A_HUMAN
• Swiss-Prot ENTRY: P85A_HUMAN
• Swiss-Prot AC number: P27986
• Sequence: P27986
• Pfam database: P85A_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P27986
• BLAST for whole protein: P27986
• SAS for whole protein: P27986
• BLAST for modular domain: 2IUI
• SAS for domain: 2IUI

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2IUI2_mat 
• iPfam: SH2
• PsiBase: 2IUI
• MINT: whole protein: P27986 or domain: 2IUI
• DOMINO database: P27986
• APID: P27986

• Title: Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.4
• Protein Source: Homo sapiens
• Reference:
• Sequence domain: seqA_2iui2.txt
• Peptide sequence of ligand: SIDXVPMLDMK
• Biochemical affinity data for: 2iui
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2IUI
• RCSB_PDB_ID: 2IUI
• SMART: SH2
• PDBsum (domain): 2IUI
• PDBsum (Ligand): 2IUI
• MSD (summary): 2IUI
• MSD (ligands): 2IUI
• Molecular Surface: 2iui

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.