INTERNAL ADAN INFORMATION

• Record: 1470
• Number: 392
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: O14757 by SMART
• Basic UniProtKB Entry: O14757
• InterPro link: O14757
• Swiss-Prot ENTRY: O14757
• Swiss-Prot AC number: O14757
• Sequence: O14757
• Pfam database: O14757

ALIGNMENT

• BLAST against Swiss-Prot: O14757
• BLAST for whole protein: O14757
• SAS for whole protein: O14757
• BLAST for modular domain: 2BRG
• SAS for domain: 2BRG

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 2BRG
• MINT: whole protein: O14757 or domain: 2BRG
• DOMINO database: O14757
• APID: O14757

• Title: Structure-Based Design of Novel Chk1 Inhibitors: Insights Into Hydrogen Bonding and Protein-Ligand Affinity.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.1
• Protein Source: Homo sapiens
• Reference: 15974586
• Sequence domain: seqA_2BRG2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2BRG
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 2BRG
• RCSB_PDB_ID: 2BRG
• SMART: kinase
• PDBsum (domain): 2BRG
• PDBsum (Ligand): 2BRG
• MSD (summary): 2BRG
• MSD (ligands): 2BRG
• Molecular Surface: 2BRG

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.