INTERNAL ADAN INFORMATION

• Record: 1466
• Number: 388
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: O14965 by SMART
• Basic UniProtKB Entry: O14965
• InterPro link: O14965
• Swiss-Prot ENTRY: O14965
• Swiss-Prot AC number: O14965
• Sequence: O14965
• Pfam database: O14965

ALIGNMENT

• BLAST against Swiss-Prot: O14965
• BLAST for whole protein: O14965
• SAS for whole protein: O14965
• BLAST for modular domain: 2BMC
• SAS for domain: 2BMC

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 2BMC
• MINT: whole protein: O14965 or domain: 2BMC
• DOMINO database: O14965
• APID: O14965

• Title: Potent and Selective Auroraa Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: 15828847
• Sequence domain: seqA_2BMC2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2BMC
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 2BMC
• RCSB_PDB_ID: 2BMC
• SMART: kinase
• PDBsum (domain): 2BMC
• PDBsum (Ligand): 2BMC
• MSD (summary): 2BMC
• MSD (ligands): 2BMC
• Molecular Surface: 2BMC

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.