INTERNAL ADAN INFORMATION

• Record: 153
• Number: 25
• Inclusion date: 21-VIII-2004

WHOLE PROTEIN INFORMATION

• Domains within protein: FYN_HUMAN by SMART
• Basic UniProtKB Entry: FYN_HUMAN
• InterPro link: FYN_HUMAN
• Swiss-Prot ENTRY: FYN_HUMAN
• Swiss-Prot AC number: P06241
• Sequence: P06241
• Pfam database: FYN_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P06241
• BLAST for whole protein: P06241
• SAS for whole protein: P06241
• BLAST for modular domain: 1AOT
• SAS for domain: 1AOT

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 1AOT2_mat 
• iPfam: SH2
• PsiBase: 1AOT
• MINT: whole protein: P06241 or domain: 1AOT
• DOMINO database: P06241
• APID: P06241

• Title: NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE
• Experimental Technique: NMR, MINIMIZED AVERAGE STRUCTURE
• Resolution Å: n/a
• Protein Source: Homo sapiens
• Reference: Mulhern et al. 1997 Structure 5, 1313
• Sequence domain: seqA_1aot2.txt
• Peptide sequence of ligand: EPQXEEIPIYL
• Biochemical affinity data for: 1aot
• Drugs:
• Phosphorylated residue type: Tyr
• Pfam family: SH2
• Pfam structure: 1AOT
• RCSB_PDB_ID: 1AOT
• SMART: SH2
• PDBsum (domain): 1AOT
• PDBsum (Ligand): 1AOT
• MSD (summary): 1AOT
• MSD (ligands): 1AOT
• Molecular Surface: 1aot

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.