INTERNAL ADAN INFORMATION

• Record: 1449
• Number: 371
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: O60674 by SMART
• Basic UniProtKB Entry: O60674
• InterPro link: O60674
• Swiss-Prot ENTRY: O60674
• Swiss-Prot AC number: O60674
• Sequence: O60674
• Pfam database: O60674

ALIGNMENT

• BLAST against Swiss-Prot: O60674
• BLAST for whole protein: O60674
• SAS for whole protein: O60674
• BLAST for modular domain: 2B7A
• SAS for domain: 2B7A

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 2B7A
• MINT: whole protein: O60674 or domain: 2B7A
• DOMINO database: O60674
• APID: O60674

• Title: The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2
• Protein Source: Homo sapiens
• Reference: 16174768
• Sequence domain: seqA_2B7A2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2B7A
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 2B7A
• RCSB_PDB_ID: 2B7A
• SMART: kinase
• PDBsum (domain): 2B7A
• PDBsum (Ligand): 2B7A
• MSD (summary): 2B7A
• MSD (ligands): 2B7A
• Molecular Surface: 2B7A

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.