INTERNAL ADAN INFORMATION

• Record: 1416
• Number: 338
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P35968 by SMART
• Basic UniProtKB Entry: P35968
• InterPro link: P35968
• Swiss-Prot ENTRY: P35968
• Swiss-Prot AC number: P35968
• Sequence: P35968
• Pfam database: P35968

ALIGNMENT

• BLAST against Swiss-Prot: P35968
• BLAST for whole protein: P35968
• SAS for whole protein: P35968
• BLAST for modular domain: 1YWN
• SAS for domain: 1YWN

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1YWN
• MINT: whole protein: P35968 or domain: 1YWN
• DOMINO database: P35968
• APID: P35968

• Title: Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.71
• Protein Source: Homo sapiens
• Reference: 15837294
• Sequence domain: seqA_1YWN2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1YWN
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1YWN
• RCSB_PDB_ID: 1YWN
• SMART: kinase
• PDBsum (domain): 1YWN
• PDBsum (Ligand): 1YWN
• MSD (summary): 1YWN
• MSD (ligands): 1YWN
• Molecular Surface: 1YWN

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.