INTERNAL ADAN INFORMATION

• Record: 1377
• Number: 299
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P30291 by SMART
• Basic UniProtKB Entry: P30291
• InterPro link: P30291
• Swiss-Prot ENTRY: P30291
• Swiss-Prot AC number: P30291
• Sequence: P30291
• Pfam database: P30291

ALIGNMENT

• BLAST against Swiss-Prot: P30291
• BLAST for whole protein: P30291
• SAS for whole protein: P30291
• BLAST for modular domain: 1X8B
• SAS for domain: 1X8B

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1X8B
• MINT: whole protein: P30291 or domain: 1X8B
• DOMINO database: P30291
• APID: P30291

• Title: Structure and inhibition of the human cell cycle checkpoint kinase, Wee1A kinase: an atypical tyrosine kinase with a key role in CDK1 regulation
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.81
• Protein Source: Homo sapiens
• Reference: 15837193
• Sequence domain: seqA_1X8B2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1X8B
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1X8B
• RCSB_PDB_ID: 1X8B
• SMART: kinase
• PDBsum (domain): 1X8B
• PDBsum (Ligand): 1X8B
• MSD (summary): 1X8B
• MSD (ligands): 1X8B
• Molecular Surface: 1X8B

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.