INTERNAL ADAN INFORMATION

• Record: 1311
• Number: 233
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: Q02750 by SMART
• Basic UniProtKB Entry: Q02750
• InterPro link: Q02750
• Swiss-Prot ENTRY: Q02750
• Swiss-Prot AC number: Q02750
• Sequence: Q02750
• Pfam database: Q02750

ALIGNMENT

• BLAST against Swiss-Prot: Q02750
• BLAST for whole protein: Q02750
• SAS for whole protein: Q02750
• BLAST for modular domain: 1S9J
• SAS for domain: 1S9J

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1S9J
• MINT: whole protein: Q02750 or domain: 1S9J
• DOMINO database: Q02750
• APID: Q02750

• Title: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.4
• Protein Source: Homo sapiens
• Reference: 15543157
• Sequence domain: seqA_1S9J2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1S9J
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1S9J
• RCSB_PDB_ID: 1S9J
• SMART: kinase
• PDBsum (domain): 1S9J
• PDBsum (Ligand): 1S9J
• MSD (summary): 1S9J
• MSD (ligands): 1S9J
• Molecular Surface: 1S9J

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.