INTERNAL ADAN INFORMATION

• Record: 1212
• Number: 134
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P0A5S4 by SMART
• Basic UniProtKB Entry: P0A5S4
• InterPro link: P0A5S4
• Swiss-Prot ENTRY: P0A5S4
• Swiss-Prot AC number: P0A5S4
• Sequence: P0A5S4
• Pfam database: P0A5S4

ALIGNMENT

• BLAST against Swiss-Prot: P0A5S4
• BLAST for whole protein: P0A5S4
• SAS for whole protein: P0A5S4
• BLAST for modular domain: 1MRU
• SAS for domain: 1MRU

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1MRU
• MINT: whole protein: P0A5S4 or domain: 1MRU
• DOMINO database: P0A5S4
• APID: P0A5S4

• Title: Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 3
• Protein Source: Mycobacterium tuberculosis
• Reference: 12548283
• Sequence domain: seqA_1MRU2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1MRU
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1MRU
• RCSB_PDB_ID: 1MRU
• SMART: kinase
• PDBsum (domain): 1MRU
• PDBsum (Ligand): 1MRU
• MSD (summary): 1MRU
• MSD (ligands): 1MRU
• Molecular Surface: 1MRU

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.