INTERNAL ADAN INFORMATION

• Record: 1202
• Number: 124
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P00533 by SMART
• Basic UniProtKB Entry: P00533
• InterPro link: P00533
• Swiss-Prot ENTRY: P00533
• Swiss-Prot AC number: P00533
• Sequence: P00533
• Pfam database: P00533

ALIGNMENT

• BLAST against Swiss-Prot: P00533
• BLAST for whole protein: P00533
• SAS for whole protein: P00533
• BLAST for modular domain: 1M17
• SAS for domain: 1M17

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1M17
• MINT: whole protein: P00533 or domain: 1M17
• DOMINO database: P00533
• APID: P00533

• Title: Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.6
• Protein Source: Homo sapiens
• Reference: 12196540
• Sequence domain: seqA_1M172.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1M17
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1M17
• RCSB_PDB_ID: 1M17
• SMART: kinase
• PDBsum (domain): 1M17
• PDBsum (Ligand): 1M17
• MSD (summary): 1M17
• MSD (ligands): 1M17
• Molecular Surface: 1M17

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.