INTERNAL ADAN INFORMATION

• Record: 1184
• Number: 106
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P08069 by SMART
• Basic UniProtKB Entry: P08069
• InterPro link: P08069
• Swiss-Prot ENTRY: P08069
• Swiss-Prot AC number: P08069
• Sequence: P08069
• Pfam database: P08069

ALIGNMENT

• BLAST against Swiss-Prot: P08069
• BLAST for whole protein: P08069
• SAS for whole protein: P08069
• BLAST for modular domain: 1K2P
• SAS for domain: 1K2P

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1K2P
• MINT: whole protein: P08069 or domain: 1K2P
• DOMINO database: P08069
• APID: P08069

• Title: Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.1
• Protein Source: Homo sapiens
• Reference: 11527964
• Sequence domain: seqA_1K2P2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1K2P
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1K2P
• RCSB_PDB_ID: 1K2P
• SMART: kinase
• PDBsum (domain): 1K2P
• PDBsum (Ligand): 1K2P
• MSD (summary): 1K2P
• MSD (ligands): 1K2P
• Molecular Surface: 1K2P

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.