INTERNAL ADAN INFORMATION

• Record: 1159
• Number: 81
• Inclusion date: 12-VI-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: P06213 by SMART
• Basic UniProtKB Entry: P06213
• InterPro link: P06213
• Swiss-Prot ENTRY: P06213
• Swiss-Prot AC number: P06213
• Sequence: P06213
• Pfam database: P06213

ALIGNMENT

• BLAST against Swiss-Prot: P06213
• BLAST for whole protein: P06213
• SAS for whole protein: P06213
• BLAST for modular domain: 1I44
• SAS for domain: 1I44

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: kinase
• PsiBase: 1I44
• MINT: whole protein: P06213 or domain: 1I44
• DOMINO database: P06213
• APID: P06213

• Title: Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.4
• Protein Source: Homo sapiens
• Reference: 11124964
• Sequence domain: seqA_1I442.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 1I44
• Drugs:
• Phosphorylated residue type:
• Pfam family: kinase
• Pfam structure: 1I44
• RCSB_PDB_ID: 1I44
• SMART: kinase
• PDBsum (domain): 1I44
• PDBsum (Ligand): 1I44
• MSD (summary): 1I44
• MSD (ligands): 1I44
• Molecular Surface: 1I44

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.