INTERNAL ADAN INFORMATION

• Record: 1059
• Number: 15
• Inclusion date: 30-V-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: PARP1_HUMAN by SMART
• Basic UniProtKB Entry: PARP1_HUMAN
• InterPro link: PARP1_HUMAN
• Swiss-Prot ENTRY: PARP1_HUMAN
• Swiss-Prot AC number: P09874
• Sequence: P09874
• Pfam database: PARP1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: P09874
• BLAST for whole protein: P09874
• SAS for whole protein: P09874
• BLAST for modular domain: 2COK
• SAS for domain: 2COK

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: BRCT
• PsiBase: 2COK
• MINT: whole protein: P09874 or domain: 2COK
• DOMINO database: P09874
• APID: P09874

• Title: Solution structure of brct domain of poly(adp-ribose) polymerase-1
• Experimental Technique: NMR 20 models
• Resolution Å:
• Protein Source: Homo sapiens
• Reference: Nagashima, T., Hayashi, F., Yokoyama, S. Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1 To be Published
• Sequence domain: seqA_2cok2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2cok
• Drugs:
• Phosphorylated residue type:
• Pfam family: BRCT
• Pfam structure: 2COK
• RCSB_PDB_ID: 2COK
• SMART: BRCT
• PDBsum (domain): 2COK
• PDBsum (Ligand): 2COK
• MSD (summary): 2COK
• MSD (ligands): 2COK
• Molecular Surface: 2cok

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.