INTERNAL ADAN INFORMATION

• Record: 1057
• Number: 13
• Inclusion date: 30-V-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: MDC1_HUMAN by SMART
• Basic UniProtKB Entry: MDC1_HUMAN
• InterPro link: MDC1_HUMAN
• Swiss-Prot ENTRY: MDC1_HUMAN
• Swiss-Prot AC number: Q14676
• Sequence: Q14676
• Pfam database: MDC1_HUMAN

ALIGNMENT

• BLAST against Swiss-Prot: Q14676
• BLAST for whole protein: Q14676
• SAS for whole protein: Q14676
• BLAST for modular domain: 2AZM
• SAS for domain: 2AZM

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2AZM2_mat 
• iPfam: BRCT
• PsiBase: 2AZM
• MINT: whole protein: Q14676 or domain: 2AZM
• DOMINO database: Q14676
• APID: Q14676

• Title: Crystal structure of the mdc1 brct repeat in complex with the histone tail of gamma-h2ax
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.41
• Protein Source: Homo sapiens
• Reference: Stucki et al., 2005 Cell 123, 1213
• Sequence domain: seqA_2azm2.txt
• Peptide sequence of ligand: ASQEY
• Biochemical affinity data for: 2azm
• Drugs:
• Phosphorylated residue type: Ser
• Pfam family: BRCT
• Pfam structure: 2AZM
• RCSB_PDB_ID: 2AZM
• SMART: BRCT
• PDBsum (domain): 2AZM
• PDBsum (Ligand): 2AZM
• MSD (summary): 2AZM
• MSD (ligands): 2AZM
• Molecular Surface: 2azm

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.