INTERNAL ADAN INFORMATION

• Record: 1020
• Number: 6
• Inclusion date: 30-V-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: TYSY_CRYNE by SMART
• Basic UniProtKB Entry: TYSY_CRYNE
• InterPro link: TYSY_CRYNE
• Swiss-Prot ENTRY: TYSY_CRYNE
• Swiss-Prot AC number: P45351
• Sequence: P45351
• Pfam database: TYSY_CRYNE

ALIGNMENT

• BLAST against Swiss-Prot: P45351
• BLAST for whole protein: P45351
• SAS for whole protein: P45351
• BLAST for modular domain: 2AAZ
• SAS for domain: 2AAZ

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: Methyl transferase
• PsiBase: 2AAZ
• MINT: whole protein: P45351 or domain: 2AAZ
• DOMINO database: P45351
• APID: P45351

• Title: Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 2.08
• Protein Source: Cryptococcus neoformans
• Reference: Finer-Moore et al., 2005 Acta Crystallogr D Biol Crystallogr. 61, 1320
• Sequence domain: seqA_2AAZ2.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2AAZ
• Drugs:
• Phosphorylated residue type:
• Pfam family: Methyl transferase
• Pfam structure: 2AAZ
• RCSB_PDB_ID: 2AAZ
• SMART: Methyl transferase
• PDBsum (domain): 2AAZ
• PDBsum (Ligand): 2AAZ
• MSD (summary): 2AAZ
• MSD (ligands): 2AAZ
• Molecular Surface: 2AAZ

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.