INTERNAL ADAN INFORMATION

• Record: 984
• Number: 76
• Inclusion date: 30-V-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: ITK_MOUSE by SMART
• Basic UniProtKB Entry: ITK_MOUSE
• InterPro link: ITK_MOUSE
• Swiss-Prot ENTRY: ITK_MOUSE
• Swiss-Prot AC number: Q03526
• Sequence: Q03526
• Pfam database: ITK_MOUSE

ALIGNMENT

• BLAST against Swiss-Prot: Q03526
• BLAST for whole protein: Q03526
• SAS for whole protein: Q03526
• BLAST for modular domain: 2EU0
• SAS for domain: 2EU0

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: 2EU02_mat 
• iPfam: SH2
• PsiBase: 2EU0
• MINT: whole protein: Q03526 or domain: 2EU0
• DOMINO database: Q03526
• APID: Q03526

• Title: The nmr ensemble structure of the itk sh2 domain bound to a phosphopeptide
• Experimental Technique: NMR, 20 models
• Resolution Å:
• Protein Source: Mus musculus
• Reference: Pletneva et al., 2006 J Mol Biol 357, 250
• Sequence domain: seqA_2eu02.txt
• Peptide sequence of ligand: ADYEPP
• Biochemical affinity data for: 2eu0
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2EU0
• RCSB_PDB_ID: 2EU0
• SMART: SH2
• PDBsum (domain): 2EU0
• PDBsum (Ligand): 2EU0
• MSD (summary): 2EU0
• MSD (ligands): 2EU0
• Molecular Surface: 2eu0

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.