INTERNAL ADAN INFORMATION

• Record: 977
• Number: 69
• Inclusion date: 30-V-2006

WHOLE PROTEIN INFORMATION

• Domains within protein: by SMART
• Basic UniProtKB Entry:
• InterPro link:
• Swiss-Prot ENTRY:
• Swiss-Prot AC number:
• Sequence:
• Pfam database:

ALIGNMENT

• BLAST against Swiss-Prot:
• BLAST for whole protein:
• SAS for whole protein:
• BLAST for modular domain: 2CI8
• SAS for domain: 2CI8

PREDICTED INTERACTIONS AND EXPERIMENTAL DATA

• FoldX Results: no ligand 
• iPfam: SH2
• PsiBase: 2CI8
• MINT: whole protein: or domain: 2CI8
• DOMINO database:
• APID:

• Title: Sh2 domain of human nck1 adaptor protein - uncomplexed
• Experimental Technique: X-RAY DIFFRACTION
• Resolution Å: 1.80
• Protein Source: Homo sapiens
• Reference: Frese, S., Schubert, W.-D., Findeis, A.C., Marquardt, T., Roske, Y.S., Stradal, T.E.B., Heinz, D.W. The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Sh2 Domains To be Published
• Sequence domain: seqA_2ci82.txt
• Peptide sequence of ligand:
• Biochemical affinity data for: 2ci8
• Drugs:
• Phosphorylated residue type:
• Pfam family: SH2
• Pfam structure: 2CI8
• RCSB_PDB_ID: 2CI8
• SMART: SH2
• PDBsum (domain): 2CI8
• PDBsum (Ligand): 2CI8
• MSD (summary): 2CI8
• MSD (ligands): 2CI8
• Molecular Surface: 2ci8

PDB1: Original Protein Data Bank file.

PDB2: Simplified coordinate files.