• Protein family: SH2
• Protein number: 3
• Peptide number: 3

Protein:

• Protein name: Crk
• Protein source: Homo Sapiens

Structural information:

• PDB apo:
• Experimental technique apo:
• Resolution apo (Å):
• PDB complex: 1ju5
• Experimental technique complex: NMR
• Resolution complex (Å):

Peptide:

• Name of peptide (in paper): Crk pY221
• Phosphorylated residue type: Tyr
• Origin protein of peptide: Crk
• Source of origin protein:
• Phosphorylated residue number in origin protein: 221
• First position before phosphorylated residue: -4
• Last position before phosphorylated residue: 7
• Sequence of peptide: EPGPpYAQPSVNT
• N-terminus: Free
• C-terminus: Free
• Peptide length: 12

Mutational information:

• wt or mutant peptide: wt
• Position of mutation in peptide:
• Mutated residue in peptide:
• New residue in peptide:
• wt or mutant protein: wt
• Position of mutation in protein:
• Mutated residue in protein:
• New residue in protein:

Thermodynamic information:

• Kdiss (mM): 37
• Km (M):
• IC50 (M):
• DGdiss (kJ/mol), experimental: -25.04
• DGdiss (kJ/mol), calculated with FOLDx:
• DDGdiss (kJ/mol):

Experimental conditions:

• Method: Radiolabeling
• Temperature ºC: 22
• pH:
• Buffer conditions:

Bibliography:

• Reference: Sawasdikosol et al. 1996 JImmun 157, 110
• MedLine_ID: 8683103