• Protein family: WW
• Protein number: 1
• Peptide number: 28

Protein:

• Protein name: Pin1
• Protein source: Homo Sapiens

Structural information:

• PDB apo: 1i6c
• Experimental technique apo: NMR, 10 structures
• Resolution apo (Å):
• PDB complex: 1f8a
• Experimental technique complex: X-ray
• Resolution complex (Å): 1.84

Peptide:

• Name of peptide (in paper): CTD
• Phosphorylated residue type: Ser
• Origin protein of peptide: Pol II CTD
• Source of origin protein: Homo Sapiens
• Phosphorylated residue number in origin protein: 2
• First position before phosphorylated residue: -1
• Last position before phosphorylated residue: 5
• Sequence of peptide: YpSPTpSPS
• N-terminus: Rhodamine
• C-terminus: Free
• Peptide length: 7

Mutational information:

• wt or mutant peptide: wt
• Position of mutation in peptide:
• Mutated residue in peptide:
• New residue in peptide:
• wt or mutant protein: wt
• Position of mutation in protein:
• Mutated residue in protein:
• New residue in protein:

Thermodynamic information:

• Kdiss (mM): 34
• Km (M):
• IC50 (M):
• DGdiss (kJ/mol), experimental: -25.24
• DGdiss (kJ/mol), calculated with FOLDx:
• DDGdiss (kJ/mol):

Experimental conditions:

• Method: Fluorescence polarization
• Temperature ºC: 22
• pH: 8
• Buffer conditions: 2 mM Tris, 1mM DTT, 0.1 mM MgCl2

Bibliography:

• Reference: Verdecia et al. 2000 NSB 7(8) 639
• MedLine_ID: 10932246