• Protein family: VHS
• Protein number: 2
• Peptide number: 2

Protein:

• Protein name: GGA3
• Protein source: Homo Sapiens

Structural information:

• PDB apo:
• Experimental technique apo:
• Resolution apo (Å):
• PDB complex: 1lf8
• Experimental technique complex: X-ray
• Resolution complex (Å): 2.3

Peptide:

• Name of peptide (in paper): CI-MPR
• Phosphorylated residue type: Ser
• Origin protein of peptide: CI-MPR
• Source of origin protein: Homo Sapiens
• Phosphorylated residue number in origin protein: 0
• First position before phosphorylated residue: -4
• Last position before phosphorylated residue: 7
• Sequence of peptide: FHDDSDEDLLHI
• N-terminus: Free
• C-terminus: Free
• Peptide length: 12

Mutational information:

• wt or mutant peptide: mutant
• Position of mutation in peptide: 0
• Mutated residue in peptide: pS
• New residue in peptide: S
• wt or mutant protein: wt
• Position of mutation in protein:
• Mutated residue in protein:
• New residue in protein:

Thermodynamic information:

• Kdiss (mM): 11
• Km (M):
• IC50 (M):
• DGdiss (kJ/mol), experimental: -28.79
• DGdiss (kJ/mol), calculated with FOLDx:
• DDGdiss (kJ/mol): 2.87

Experimental conditions:

• Method: ITC
• Temperature ºC: 30
• pH: 7.5
• Buffer conditions: 50 mM Phosphate, 100 mM NaCl, 1 mM DTT

Bibliography:

• Reference: Kato et al. 2002 NSB 9(7) 532
• MedLine_ID: 12032548