• Protein family: SH2
• Protein number: 10
• Peptide number: 86

Protein:

• Protein name: Lck
• Protein source: Homo Sapiens

Structural information:

• PDB apo: 1bhh
• Experimental technique apo: X-ray
• Resolution apo (Å): 1.9
• PDB complex: 1bhh
• Experimental technique complex: X-ray
• Resolution complex (Å): 1

Peptide:

• Name of peptide (in paper): peptide1
• Phosphorylated residue type: Tyr
• Origin protein of peptide: middle T
• Source of origin protein: Polyoma Virus
• Phosphorylated residue number in origin protein: 324
• First position before phosphorylated residue: 0
• Last position before phosphorylated residue: 3
• Sequence of peptide: pYEEI
• N-terminus: Acetylated
• C-terminus: Free
• Peptide length: 4

Mutational information:

• wt or mutant peptide: wt
• Position of mutation in peptide:
• Mutated residue in peptide:
• New residue in peptide:
• wt or mutant protein: wt
• Position of mutation in protein:
• Mutated residue in protein:
• New residue in protein:

Thermodynamic information:

• Kdiss (mM): 0.1
• Km (M):
• IC50 (M):
• DGdiss (kJ/mol), experimental: -39.28
• DGdiss (kJ/mol), calculated with FOLDx:
• DDGdiss (kJ/mol):

Experimental conditions:

• Method: SPR
• Temperature ºC: 20
• pH:
• Buffer conditions:

Bibliography:

• Reference: Llinas-Brunet et al. 1999 JMedChem 42, 722
• MedLine_ID: 10052978