Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1ZUY-29.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8 9 10
poly-Ala
A
A
 A
A
 A A A
A
A
A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 1.064 ΔGbinding -0.494
TOTAL
 0.570
Backbone Hb 0.000 Cis_bond 0.000
Sidechain Hb -0.000 Torsional clash 0.466
Van der Waals -3.537 Backbone clash 0.008
Electrostatics 0.062 Helix dipole 0.000
Solvation Polar 3.820 Water bridges -0.066
Solvation Hyd -4.611 Disulfide 0.000
VdW clashes 0.143 Electrost. Kon 0.080
Entropy sc 0.217 Part.cov.bonds 0.000
Entropy mc

2.931

 ΔGstability

8.653
       

Predicted ligand sequences for model [MYO5_1ZUY-29.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1ZUY-29.PDB  

(data)
# Predicted Sequences Value Calculate
1 RRMPLPFRWH 0.0
2 RRPPLPFRWH 0.0
3 RRMPMPFRWH 0.01
4 RRPPMPFRWH 0.01
5 HRMPLPFRWH 0.03
6 HRPPLPFRWH 0.03
7 HRMPMPFRWH 0.04
8 HRPPMPFRWH 0.04
9 RRMPLPFRWR 0.05
10 KRMPLPFRWH 0.05
11 RYMPLPFRWH 0.05
12 KRPPLPFRWH 0.05
13 KRPPMPFRWH 0.06
14 RRMPMPFRWR 0.06
15 RYMPMPFRWH 0.06
16 RRPPLPFRWR 0.06
17 KRMPMPFRWH 0.06
18 RRPPMPFRWR 0.06
19 RYPPMPFRWH 0.06
20 RYPPLPFRWH 0.06
21 HRMPLPFRWR 0.08
22 HYMPLPFRWH 0.08
23 HYPPLPFRWH 0.09
24 HYMPMPFRWH 0.09
25 HYPPMPFRWH 0.09
26 HRMPMPFRWR 0.09
27 HRPPMPFRWR 0.09
28 HRPPLPFRWR 0.09
29 KRMPLPFRWR 0.1
30 KRPPLPFRWR 0.1
31 RYMPLPFRWR 0.1
32 KYMPLPFRWH 0.1
33 RYMPMPFRWR 0.11
34 KRPPMPFRWR 0.11
35 KYMPMPFRWH 0.11
36 KRMPMPFRWR 0.11
37 KYPPMPFRWH 0.11
38 KYPPLPFRWH 0.11
39 RYPPLPFRWR 0.11
40 RYPPMPFRWR 0.12
41 HYMPLPFRWR 0.13
42 HYPPLPFRWR 0.14
43 HYMPMPFRWR 0.14
44 RRMMLPFRWH 0.14
45 KYMPLPFRWR 0.15
46 RRMMMPFRWH 0.15
47 HYPPMPFRWR 0.15
48 RRPMMPFRWH 0.15
49 RRPMLPFRWH 0.15
50 KYMPMPFRWR 0.16
51 KYPPMPFRWR 0.16
52 KYPPLPFRWR 0.16
53 HRMMLPFRWH 0.17
54 HRPMMPFRWH 0.18
55 HRMMMPFRWH 0.18
56 HRPMLPFRWH 0.18
57 KRMMLPFRWH 0.19
58 RRMWLPFRWH 0.19
59 KRMMMPFRWH 0.2
60 RYPMLPFRWH 0.2
61 KRPMLPFRWH 0.2
62 RRMWMPFRWH 0.2
63 RRPWLPFRWH 0.2
64 RRMMMPFRWR 0.2
65 RYMMLPFRWH 0.2
66 RYMMMPFRWH 0.2
67 KRPMMPFRWH 0.2
68 RRMMLPFRWR 0.2
69 RRPMLPFRWR 0.2
70 RYPMMPFRWH 0.21
71 RRPWMPFRWH 0.21
72 RRPMMPFRWR 0.21
73 HRMWLPFRWH 0.22
74 HYMMMPFRWH 0.23
75 HYPMLPFRWH 0.23
76 HYMMLPFRWH 0.23
77 RRLPLPFRWH 0.23
78 RRLPMPFRWH 0.23
79 HRMMMPFRWR 0.23
80 HRMMLPFRWR 0.23
81 HRMWMPFRWH 0.23
82 HRPWLPFRWH 0.23
83 HRPMLPFRWR 0.23
84 HRPMMPFRWR 0.24
85 HYPMMPFRWH 0.24
86 KRMWLPFRWH 0.24
87 HRPWMPFRWH 0.24
88 KRMMLPFRWR 0.24
89 KYMMLPFRWH 0.24
90 RYPMLPFRWR 0.25
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

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# Precalculated Models Intraclash ΔGbinding Total
1 RRMPMPFRWR

2.64

-10.43

-7.79
2 HYMPMPFRWH

3.33

-10.69

-7.36
3 KRMPMPFRWH

2.7

-10.03

-7.33
4 RRMPLPFRWR

3.76

-10.98

-7.22
5 RRMPLPFRWH

3.61

-10.76

-7.15
6 RRMPMPFRWH

3.28

-10.4

-7.12
7 KRMPLPFRWR

3.41

-10.46

-7.05
8 HYPPMPFRWH

3.26

-9.85

-6.59
9 KRPPLPFRWR

2.5

-9.07

-6.57
10 HRMPLPFRWR

3.66

-10.22

-6.56
11 KRMPLPFRWH

3.64

-10.04

-6.4
12 HRMPLPFRWH

3.48

-9.84

-6.36
13 KRPPMPFRWH

3.26

-9.52

-6.26
14 RRPPMPFRWH

3.9

-10.07

-6.17
15 HRPPMPFRWH

3.38

-9.26

-5.88
16 HRPPLPFRWR

3.28

-9.07

-5.79
17 HRPPLPFRWH

3.38

-9.11

-5.73
18 RRPPMPFRWR

3.54

-9.22

-5.68
19 KRPPLPFRWH

3.33

-8.93

-5.6
20 RRPPLPFRWR

3.29

-8.88

-5.59
21 HRMPMPFRWH

3.65

-9.14

-5.49
22 RYMPMPFRWH

3.25

-8.73

-5.48
23 RRPPLPFRWH

3.52

-8.89

-5.37
24 HYMPLPFRWH

3.76

-9.05

-5.29
25 RYMPLPFRWH

3.47

-8.75

-5.28
26 HRMPMPFRWR

3.74

-8.99

-5.25
27 HRPPMPFRWR

3.45

-8.25

-4.8
28 RYPPMPFRWH

2.96

-7.73

-4.77
29 RYPPLPFRWH

3.58

-7.68

-4.1
30 HYPPLPFRWH

3.49

-7.19

-3.7

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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