Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1YP5-9.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8
poly-Ala
A
 A
A
 A
A
 A
A
A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 1.636 ΔGbinding 1.057
TOTAL
 2.693
Backbone Hb -1.275 Cis_bond 0.000
Sidechain Hb -1.275 Torsional clash 0.413
Van der Waals -3.857 Backbone clash 2.817
Electrostatics 0.127 Helix dipole 0.000
Solvation Polar 4.604 Water bridges 0.022
Solvation Hyd -4.915 Disulfide 0.000
VdW clashes 2.000 Electrost. Kon 0.170
Entropy sc 0.829 Part.cov.bonds 0.000
Entropy mc

4.213

 ΔGstability

11.186
       

Predicted ligand sequences for model [MYO5_1YP5-9.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1YP5-9.PDB  

(data)
# Predicted Sequences Value Calculate
1 KRPRPPRK 0.0
2 KRWRPPRK 0.01
3 KRPIPPRK 0.03
4 KRWIPPRK 0.04
5 KRFRPPRK 0.06
6 KRPRPLRK 0.08
7 KRFIPPRK 0.09
8 KRWRPLRK 0.09
9 RRPRPPRK 0.09
10 KRPIPLRK 0.1
11 RRWRPPRK 0.11
12 KRWIPLRK 0.11
13 RRPIPPRK 0.12
14 RRWIPPRK 0.13
15 KRFRPLRK 0.13
16 RRFRPPRK 0.15
17 KRFIPLRK 0.16
18 RRPRPLRK 0.17
19 KRPRPDRK 0.18
20 RRWRPLRK 0.18
21 RRFIPPRK 0.18
22 KRWRPDRK 0.19
23 KRPMPPRK 0.19
24 RRPIPLRK 0.2
25 KRWMPPRK 0.2
26 KRPIPDRK 0.21
27 RRWIPLRK 0.21
28 KRWIPDRK 0.22
29 RRFRPLRK 0.23
30 KRFRPDRK 0.24
31 KRFMPPRK 0.25
32 RRFIPLRK 0.26
33 KRFIPDRK 0.27
34 KRPMPLRK 0.27
35 RRPRPDRK 0.28
36 KRWMPLRK 0.28
37 RRWRPDRK 0.29
38 RRPMPPRK 0.29
39 RRPIPDRK 0.3
40 RRWMPPRK 0.3
41 RRWIPDRK 0.31
42 KRFMPLRK 0.33
43 RRFRPDRK 0.33
44 RRFMPPRK 0.34
45 RRPMPLRK 0.36
46 KMPRPPRK 0.36
47 RRFIPDRK 0.36
48 KRPMPDRK 0.37
49 RRWMPLRK 0.37
50 KMWRPPRK 0.38
51 KRWMPDRK 0.39
52 KMPIPPRK 0.39
53 KMWIPPRK 0.4
54 KMFRPPRK 0.42
55 RRFMPLRK 0.42
56 KFPRPPRK 0.42
57 KRFMPDRK 0.43
58 KFWRPPRK 0.43
59 KMPRPLRK 0.44
60 KMWRPLRK 0.45
61 KFPIPPRK 0.45
62 KMFIPPRK 0.45
63 KFWIPPRK 0.46
64 RMPRPPRK 0.46
65 RRPMPDRK 0.47
66 RMWRPPRK 0.47
67 KMPIPLRK 0.47
68 KFFRPPRK 0.48
69 KMWIPLRK 0.48
70 RRWMPDRK 0.48
71 RMPIPPRK 0.49
72 KFPRPLRK 0.5
73 KMFRPLRK 0.5
74 RMWIPPRK 0.5
75 KFFIPPRK 0.51
76 RFPRPPRK 0.51
77 KFWRPLRK 0.51
78 RMFRPPRK 0.52
79 RRFMPDRK 0.52
80 KFPIPLRK 0.52
81 RFWRPPRK 0.53
82 KMFIPLRK 0.53
83 RMPRPLRK 0.53
84 RMFIPPRK 0.54
85 RFPIPPRK 0.54
86 KFWIPLRK 0.54
87 RFWIPPRK 0.55
88 KFFRPLRK 0.55
89 RMWRPLRK 0.55
90 KMPRPDRK 0.55
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

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# Precalculated Models Intraclash ΔGbinding Total
1 RRFIPPRK

1.12

-9.77

-8.65
2 RRPIPPRK

1.16

-8.26

-7.1
3 KRWIPDRK

1.22

-7.96

-6.74
4 RRWRPPRK

1.33

-7.99

-6.66
5 RRPRPPRK

1.2

-7.85

-6.65
6 KRWMPPRK

1.17

-7.81

-6.64
7 KRPMPPRK

1.12

-7.76

-6.64
8 RRWIPLRK

1.17

-7.77

-6.6
9 RRFRPLRK

1.3

-7.87

-6.57
10 KRPIPDRK

1.12

-7.67

-6.55
11 RRPRPLRK

1.4

-7.9

-6.5
12 RRPIPLRK

1.23

-7.66

-6.43
13 KRPIPPRK

1.09

-7.51

-6.42
14 KRWRPDRK

1.19

-7.6

-6.41
15 RRFRPPRK

1.31

-7.66

-6.35
16 RRWIPPRK

1.53

-7.86

-6.33
17 KRFRPPRK

1.1

-7.4

-6.3
18 KRPRPDRK

1.06

-7.27

-6.21
19 RRWRPLRK

1.14

-7.25

-6.11
20 KRPIPLRK

1.05

-7.16

-6.11
21 KRFIPPRK

1.17

-7.24

-6.07
22 KRWIPPRK

1.48

-7.55

-6.07
23 KRFIPLRK

1.08

-7.13

-6.05
24 KRFRPDRK

1.38

-7.33

-5.95
25 KRWIPLRK

1.17

-7.12

-5.95
26 KRFRPLRK

1.12

-7.02

-5.9
27 KRPRPPRK

1.08

-6.73

-5.65
28 KRWRPPRK

1.34

-6.93

-5.59
29 KRWRPLRK

1.3

-6.83

-5.53
30 KRPRPLRK

1.1

-6.34

-5.24

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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