Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1YP5-6.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8 9 10
poly-Ala
A
 A
A
 A
A
A
A
A
A
A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 1.910 ΔGbinding 4.078
TOTAL
 5.988
Backbone Hb 0.000 Cis_bond 0.000
Sidechain Hb 0.000 Torsional clash 1.246
Van der Waals -3.712 Backbone clash 3.300
Electrostatics 0.057 Helix dipole 0.000
Solvation Polar 4.068 Water bridges -0.070
Solvation Hyd -4.886 Disulfide 0.000
VdW clashes 4.244 Electrost. Kon 0.054
Entropy sc 0.284 Part.cov.bonds 0.000
Entropy mc

2.792

 ΔGstability

17.009
       

Predicted ligand sequences for model [MYO5_1YP5-6.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1YP5-6.PDB  

(data)
# Predicted Sequences Value Calculate
1 DRKIGWRRPR 0.0
2 DRRIGWRRPR 0.03
3 DRKIGFRRPR 0.09
4 DRRIGFRRPR 0.12
5 DPKIGWRRPR 0.16
6 DRKKGWRRPR 0.16
7 DRKMGWRRPR 0.17
8 DPRIGWRRPR 0.18
9 DRRKGWRRPR 0.19
10 DRRMGWRRPR 0.2
11 DRKIGLRRPR 0.21
12 DRIIGWRRPR 0.21
13 DFKIGWRRPR 0.23
14 DRRIGLRRPR 0.24
15 DRKKGFRRPR 0.25
16 DPKIGFRRPR 0.25
17 DRKMGFRRPR 0.26
18 DRKIGWRRMR 0.26
19 DFRIGWRRPR 0.26
20 DRRKGFRRPR 0.28
21 DPRIGFRRPR 0.28
22 DRRIGWRRMR 0.28
23 DRRMGFRRPR 0.29
24 DRKIGWRRRR 0.3
25 DRIIGFRRPR 0.3
26 DPKKGWRRPR 0.32
27 DRKIGWRRPK 0.32
28 DPKMGWRRPR 0.33
29 DRRIGWRRRR 0.33
30 DFKIGFRRPR 0.33
31 DPRKGWRRPR 0.34
32 DRKIGFRRMR 0.35
33 DPRMGWRRPR 0.35
34 DRRIGWRRPK 0.35
35 DFRIGFRRPR 0.36
36 DPIIGWRRPR 0.37
37 DRIKGWRRPR 0.37
38 DRKKGLRRPR 0.37
39 DPKIGLRRPR 0.37
40 DRRIGFRRMR 0.38
41 DRKMGLRRPR 0.38
42 DRIMGWRRPR 0.38
43 DRKIGFRRRR 0.39
44 DPRIGLRRPR 0.4
45 DFKKGWRRPR 0.4
46 DRRKGLRRPR 0.4
47 DFKMGWRRPR 0.41
48 DPKIGWRRMR 0.41
49 DRKIGFRRPK 0.41
50 DRRMGLRRPR 0.41
51 DPKKGFRRPR 0.41
52 DPKMGFRRPR 0.42
53 DFRKGWRRPR 0.42
54 DRKKGWRRMR 0.42
55 DRIIGLRRPR 0.42
56 DRRIGFRRRR 0.42
57 DFRMGWRRPR 0.43
58 DRKMGWRRMR 0.43
59 DPRIGWRRMR 0.44
60 DRRIGFRRPK 0.44
61 DPRKGFRRPR 0.44
62 DRRKGWRRMR 0.44
63 DFIIGWRRPR 0.45
64 DPRMGFRRPR 0.45
65 DFKIGLRRPR 0.45
66 DPKIGWRRRR 0.45
67 DRRMGWRRMR 0.45
68 NRKIGWRRPR 0.46
69 DPIIGFRRPR 0.46
70 DRIKGFRRPR 0.46
71 DRKKGWRRRR 0.46
72 DRIIGWRRMR 0.47
73 DRKIGLRRMR 0.47
74 DRKMGWRRRR 0.47
75 DRIMGFRRPR 0.47
76 DPKIGWRRPK 0.48
77 DFRIGLRRPR 0.48
78 DPRIGWRRRR 0.48
79 DRKKGWRRPK 0.48
80 DRKMGWRRPK 0.49
81 NRRIGWRRPR 0.49
82 DFKKGFRRPR 0.49
83 DRRKGWRRRR 0.49
84 DFKIGWRRMR 0.49
85 DPKIGFRRMR 0.5
86 DRRMGWRRRR 0.5
87 DRRIGLRRMR 0.5
88 DFKMGFRRPR 0.5
89 DPRIGWRRPK 0.51
90 DRIIGWRRRR 0.51
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

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# Precalculated Models Intraclash ΔGbinding Total
1 DPKKGWRRPR

1.3

-5.66

-4.36
2 DPKMGWRRPR

1.29

-5.64

-4.35
3 DRRKGFRRPR

1.54

-5.78

-4.24
4 DRIIGFRRPR

1.22

-4.97

-3.75
5 DRRIGWRRPR

1.48

-5.21

-3.73
6 DRRKGWRRPR

1.67

-5.38

-3.71
7 DPRIGWRRPR

1.42

-5.13

-3.71
8 DRRIGWRRMR

1.15

-4.76

-3.61
9 DRKIGWRRMR

1.2

-4.76

-3.56
10 DPRIGFRRPR

1.08

-4.58

-3.5
11 DRRIGFRRPR

1.5

-4.99

-3.49
12 DPKIGWRRPR

1.41

-4.84

-3.43
13 DRKIGWRRRR

1.35

-4.73

-3.38
14 DRRMGWRRPR

1.44

-4.81

-3.37
15 DRKMGFRRPR

1.72

-5.08

-3.36
16 DPKIGFRRPR

1.23

-4.58

-3.35
17 DRKIGWRRPR

1.52

-4.83

-3.31
18 DRRIGWRRRR

1.48

-4.75

-3.27
19 DRIIGWRRPR

1.45

-4.69

-3.24
20 DRKIGFRRPR

1.53

-4.77

-3.24
21 DRKMGWRRPR

1.57

-4.67

-3.1
22 DRKIGWRRPK

1.37

-4.37

-3.0
23 DFKIGFRRPR

1.1

-4.09

-2.99
24 DRKKGFRRPR

1.99

-4.97

-2.98
25 DRRIGLRRPR

1.72

-4.69

-2.97
26 DRKIGLRRPR

1.57

-4.54

-2.97
27 DRRMGFRRPR

1.75

-4.72

-2.97
28 DRKKGWRRPR

1.6

-4.47

-2.87
29 DFRIGWRRPR

1.49

-4.3

-2.81
30 DFKIGWRRPR

1.69

-4.18

-2.49

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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