Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1YP5-5.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8 9 10
poly-Ala
A
 A
A
A
 A
A
 A A
A
 A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 0.916 ΔGbinding -3.445
TOTAL
 -2.529
Backbone Hb -1.462 Cis_bond 0.000
Sidechain Hb -1.463 Torsional clash 1.390
Van der Waals -5.922 Backbone clash 0.163
Electrostatics -0.600 Helix dipole 0.000
Solvation Polar 6.851 Water bridges -0.050
Solvation Hyd -8.192 Disulfide 0.000
VdW clashes 1.003 Electrost. Kon -0.626
Entropy sc 1.413 Part.cov.bonds 0.000
Entropy mc

4.212

 ΔGstability

5.041
       

Predicted ligand sequences for model [MYO5_1YP5-5.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1YP5-5.PDB  

(data)
# Predicted Sequences Value Calculate
1 FYNWPRWDHF 0.0
2 FYNWPRPDHF 0.01
3 FYNWPRMDHF 0.04
4 FYNWPRWDHW 0.05
5 FYNWPRPDHW 0.06
6 FYNWDRWDHF 0.09
7 FYNWPRWDHP 0.09
8 FYNWPRMDHW 0.09
9 FYNWDRPDHF 0.1
10 FYNWPRPDHP 0.1
11 FYNWLRWDHF 0.13
12 FYNWLRPDHF 0.13
13 FYNWPRMDHP 0.13
14 FYNWDRWDHW 0.14
15 FYNWDRMDHF 0.14
16 FYNWDRPDHW 0.15
17 FYNWPRWPHF 0.15
18 FYNWPRPPHF 0.16
19 FYNWLRMDHF 0.17
20 FYNWDRWDHP 0.18
21 FYNWDRMDHW 0.18
22 FYNWLRWDHW 0.18
23 FYNWLRPDHW 0.18
24 FYNWDRPDHP 0.19
25 FYQWPRWDHF 0.19
26 FYNWPRMPHF 0.19
27 FYQWPRPDHF 0.2
28 FYNWPRWPHW 0.2
29 FYNWPRPPHW 0.21
30 FYNWDRMDHP 0.22
31 FYNWLRWDHP 0.22
32 FYNWLRPDHP 0.22
33 FYNWLRMDHW 0.22
34 FYNWDRWPHF 0.24
35 FYQWPRMDHF 0.24
36 FYQWPRWDHW 0.24
37 FYNWPRMPHW 0.24
38 FYNWPRWPHP 0.24
39 FYNWDRPPHF 0.25
40 FYNWPRPPHP 0.25
41 FYQWPRPDHW 0.25
42 FYNWLRMDHP 0.26
43 FYQWPRMDHW 0.28
44 FYQWPRWDHP 0.28
45 FYNWLRWPHF 0.28
46 FYNWPRMPHP 0.28
47 FYNWDRWPHW 0.29
48 FYQWPRPDHP 0.29
49 FYNWDRMPHF 0.29
50 FYQWDRPDHF 0.29
51 FYNWLRPPHF 0.29
52 FYQWDRWDHF 0.29
53 FYNWDRPPHW 0.3
54 FYNWLRMPHF 0.32
55 FYQWPRMDHP 0.32
56 FYQWLRWDHF 0.32
57 FYQWLRPDHF 0.33
58 FYNWDRWPHP 0.33
59 FYNWLRWPHW 0.33
60 FINWPRWDHF 0.33
61 FYQWDRMDHF 0.33
62 FYNWDRPPHP 0.34
63 FYQWPRWPHF 0.34
64 FINWPRPDHF 0.34
65 FYNWDRMPHW 0.34
66 FYNWLRPPHW 0.34
67 FYQWDRPDHW 0.34
68 FYQWDRWDHW 0.34
69 FYQWPRPPHF 0.35
70 FYQWLRMDHF 0.36
71 FPNWPRWDHF 0.37
72 FYNWPRWDKF 0.37
73 FINWPRMDHF 0.37
74 FYNWLRMPHW 0.37
75 FYNWLRWPHP 0.37
76 FYQWLRWDHW 0.37
77 FYQWLRPDHW 0.38
78 FPNWPRPDHF 0.38
79 FYNWPRPDKF 0.38
80 FINWPRWDHW 0.38
81 FYNWDRMPHP 0.38
82 FYNWLRPPHP 0.38
83 FYQWDRMDHW 0.38
84 FYQWDRPDHP 0.38
85 FYQWDRWDHP 0.38
86 FINWPRPDHW 0.39
87 FYQWPRWPHW 0.39
88 FYQWPRMPHF 0.39
89 FYNRPRPDHF 0.4
90 FYQWPRPPHW 0.4
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

(Help)
# Precalculated Models Intraclash ΔGbinding Total
1 FYNWDRPDHF

1.45

-8.64

-7.19
2 FYNWDRPDHW

1.72

-8.87

-7.15
3 FYQWPRPDHF

1.35

-8.47

-7.12
4 FYNWDRMDHF

1.62

-8.62

-7.0
5 FYNWPRPDHW

1.48

-8.47

-6.99
6 FYNWPRPDHP

1.52

-8.43

-6.91
7 FYNWPRPDHF

1.22

-8.12

-6.9
8 FYNWDRMDHW

1.75

-8.58

-6.83
9 FYNWLRPDHW

1.44

-8.26

-6.82
10 FYNWPRMDHF

1.35

-8.16

-6.81
11 FYNWPRPPHF

1.42

-8.18

-6.76
12 FYNWPRPPHW

1.61

-8.15

-6.54
13 FYNWLRPDHF

1.56

-8.02

-6.46
14 FYNWPRMDHW

1.51

-7.45

-5.94
15 FYNWDRPDHP

1.76

-7.68

-5.92
16 FYQWPRWDHF

2.45

-8.34

-5.89
17 FYNWLRMDHF

1.75

-7.46

-5.71
18 FYNWPRMPHF

1.32

-7.01

-5.69
19 FYNWPRWDHF

2.19

-7.86

-5.67
20 FYNWPRWPHW

2.42

-7.77

-5.35
21 FYNWPRMDHP

1.4

-6.63

-5.23
22 FYNWDRWDHW

2.52

-7.66

-5.14
23 FYNWDRWDHF

2.17

-7.17

-5.0
24 FYNWLRWDHW

2.14

-7.06

-4.92
25 FYNWLRWDHF

2.25

-7.16

-4.91
26 FYNWPRWDHW

2.33

-6.9

-4.57
27 FYNWPRWPHF

2.33

-6.82

-4.49
28 FYNWPRWDHP

2.06

-6.19

-4.13
29 FYNWDRWDHP

2.98

-6.18

-3.2
30 FYNWDRMDHP

3.22

-5.8

-2.58

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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