Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1RUW-1.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8 9 10
poly-Ala
A
A
A
A
A
 A
A
 A
A
A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 0.321 ΔGbinding -1.850
TOTAL
 -1.529
Backbone Hb -1.275 Cis_bond 0.000
Sidechain Hb -1.275 Torsional clash 0.938
Van der Waals -4.453 Backbone clash 0.121
Electrostatics -0.158 Helix dipole 0.000
Solvation Polar 4.825 Water bridges -0.000
Solvation Hyd -6.294 Disulfide 0.000
VdW clashes 2.991 Electrost. Kon -0.221
Entropy sc 0.799 Part.cov.bonds 0.000
Entropy mc

2.273

 ΔGstability

3.592
       

Predicted ligand sequences for model [MYO5_1RUW-1.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1RUW-1.PDB  

(data)
# Predicted Sequences Value Calculate
1 RKSRDHMDRF 0.0
2 RKLRDHMDRF 0.01
3 RKRRDHMDRF 0.03
4 RKSRRHMDRF 0.03
5 RKLRRHMDRF 0.05
6 RKSRMHMDRF 0.07
7 RKRRRHMDRF 0.07
8 RKLRMHMDRF 0.08
9 RKRRMHMDRF 0.1
10 RKSRDHMRRF 0.17
11 RKLRDHMRRF 0.19
12 RKRRDHMRRF 0.2
13 RKSRRHMRRF 0.21
14 RKLRRHMRRF 0.22
15 RKSRDFMDRF 0.22
16 RKLRDFMDRF 0.23
17 RKSRMHMRRF 0.24
18 RKRRRHMRRF 0.24
19 RKSRRFMDRF 0.25
20 RKRRDFMDRF 0.25
21 RKLRMHMRRF 0.25
22 RKLRRFMDRF 0.27
23 RKRRMHMRRF 0.27
24 RKRRRFMDRF 0.28
25 RKSRMFMDRF 0.28
26 RKSRDHMKRF 0.29
27 RKLRMFMDRF 0.3
28 RKLRDHMKRF 0.3
29 RKSRRHMKRF 0.32
30 RKRRMFMDRF 0.32
31 RKRRDHMKRF 0.32
32 RKSRDMMDRF 0.34
33 RKLRRHMKRF 0.34
34 RKSRMHMKRF 0.35
35 RKLRDMMDRF 0.36
36 RKRRRHMKRF 0.36
37 RKLRMHMKRF 0.37
38 RKRRDMMDRF 0.38
39 RKSRRMMDRF 0.38
40 RKSRDFMRRF 0.39
41 RKRRMHMKRF 0.39
42 RKLRRMMDRF 0.39
43 RKLRDFMRRF 0.4
44 RKRRRMMDRF 0.41
45 RKSRMMMDRF 0.41
46 RKLRMMMDRF 0.42
47 RKSRRFMRRF 0.42
48 RKRRDFMRRF 0.42
49 RKRRMMMDRF 0.44
50 RKLRRFMRRF 0.44
51 RKSRDHRDRF 0.44
52 RKRRRFMRRF 0.46
53 RKLRDHRDRF 0.46
54 RKSRMFMRRF 0.46
55 RKRRDHRDRF 0.47
56 RKLRMFMRRF 0.47
57 RKSRRHRDRF 0.48
58 RKLRRHRDRF 0.49
59 RKRRMFMRRF 0.49
60 RKSRDFMKRF 0.51
61 RKRRRHRDRF 0.51
62 RKSRMHRDRF 0.51
63 RKLRMHRDRF 0.52
64 RKLRDFMKRF 0.52
65 RKSRDMMRRF 0.52
66 RKLRDMMRRF 0.53
67 RKRRMHRDRF 0.54
68 RKSRRFMKRF 0.54
69 RKRRDFMKRF 0.54
70 RKLRRFMKRF 0.55
71 RKSRRMMRRF 0.55
72 RKRRDMMRRF 0.55
73 RKLRRMMRRF 0.56
74 RKRRRFMKRF 0.57
75 RKSRMFMKRF 0.57
76 RKSRMMMRRF 0.58
77 RKRRRMMRRF 0.58
78 RKLRMFMKRF 0.59
79 RKRRMFMKRF 0.6
80 RKLRMMMRRF 0.6
81 RKSRDHRRRF 0.61
82 RKRRMMMRRF 0.61
83 RKSRDMMKRF 0.63
84 RKLRDHRRRF 0.63
85 RKRRDHRRRF 0.65
86 RKSRRHRRRF 0.65
87 RKLRDMMKRF 0.65
88 RKSRDFRDRF 0.66
89 RKLRRHRRRF 0.66
90 RKRRDMMKRF 0.67
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

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# Precalculated Models Intraclash ΔGbinding Total
1 RKLRDHMDRF

1.81

-9.88

-8.07
2 RKLRDHMRRF

1.9

-9.53

-7.63
3 RKRRDHMRRF

1.97

-9.48

-7.51
4 RKSRMHMRRF

1.82

-9.28

-7.46
5 RKSRDHMDRF

1.99

-9.37

-7.38
6 RKRRMHMRRF

1.88

-9.0

-7.12
7 RKLRRHMRRF

1.96

-8.94

-6.98
8 RKSRDHMKRF

2.04

-8.99

-6.95
9 RKSRRHMRRF

2.11

-8.9

-6.79
10 RKRRDHMDRF

1.85

-8.63

-6.78
11 RKLRRHMDRF

2.05

-8.7

-6.65
12 RKSRDHMRRF

2.22

-8.84

-6.62
13 RKRRRHMRRF

2.0

-8.59

-6.59
14 RKRRMHMDRF

1.78

-8.32

-6.54
15 RKSRRHMKRF

2.1

-8.6

-6.5
16 RKRRRFMDRF

2.38

-8.82

-6.44
17 RKLRDFMDRF

2.46

-8.85

-6.39
18 RKLRMFMDRF

2.27

-8.43

-6.16
19 RKSRMHMDRF

1.76

-7.86

-6.1
20 RKLRDHMKRF

2.33

-8.41

-6.08
21 RKLRMHMDRF

1.79

-7.83

-6.04
22 RKRRDFMDRF

2.62

-8.47

-5.85
23 RKSRDFMDRF

2.49

-8.08

-5.59
24 RKLRRFMDRF

2.42

-7.94

-5.52
25 RKRRMFMDRF

2.45

-7.89

-5.44
26 RKRRRHMDRF

1.99

-7.34

-5.35
27 RKSRRHMDRF

1.94

-7.25

-5.31
28 RKSRMFMDRF

2.39

-7.64

-5.25
29 RKSRRFMDRF

2.34

-7.26

-4.92
30 RKLRMHMRRF

1.91

-6.7

-4.79

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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