Predicted ligand sequences (modelled structure)


ADAN-name: MYO5_1R6S-1.PDB (view again the scoring matrix)

Starting poly-Ala ligand sequence and binding properties                 (Help)

position 1 2 3 4 5 6 7 8 9 10
poly-Ala
A
A
A
A
A
 A A A A A

Grey: Restrictive positions; only 1 or 2 residues predicted after FoldX analysis

Yellow: Tolerant positions; more than 10 residues predicted after FoldX analysis

 

WT ligand    

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Intraclash 0.189 ΔGbinding -4.092
TOTAL
 -3.903
Backbone Hb -1.275 Cis_bond 0.000
Sidechain Hb -1.275 Torsional clash 0.957
Van der Waals -4.360 Backbone clash 0.122
Electrostatics -0.210 Helix dipole 0.000
Solvation Polar 4.771 Water bridges -0.052
Solvation Hyd -6.176 Disulfide 0.000
VdW clashes 0.885 Electrost. Kon -0.274
Entropy sc 0.896 Part.cov.bonds 0.000
Entropy mc

2.022

 ΔGstability

4.698
       

Predicted ligand sequences for model [MYO5_1R6S-1.PDB]

(from FoldX scoring matrices).
If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence).
 
  MYO5_1R6S-1.PDB  

(data)
# Predicted Sequences Value Calculate
1 RRSKRIMDRY 0.0
2 RRRKRIMDRY 0.02
3 RRLKRIMDRY 0.03
4 RRSKRIPDRY 0.06
5 RRSRRIMDRY 0.08
6 RRLKRIPDRY 0.08
7 RRRKRIPDRY 0.08
8 RRRRRIMDRY 0.1
9 RRLRRIMDRY 0.1
10 RRSKRIMDKY 0.11
11 RRSKRIMDRF 0.12
12 RRSKRIMRRY 0.12
13 RRSRRIPDRY 0.13
14 RRRKRIMDKY 0.13
15 RRRKRIMDRF 0.14
16 RRLKRIMDRF 0.14
17 RRSKRHMDRY 0.14
18 RRLKRIMDKY 0.14
19 RRRKRIMRRY 0.15
20 RRRRRIPDRY 0.15
21 RRLKRIMRRY 0.15
22 RRSKRRMDRY 0.16
23 RRLRRIPDRY 0.16
24 RRLKRHMDRY 0.17
25 RRRKRHMDRY 0.17
26 RRSKRIPDKY 0.17
27 RRSKRIPDRF 0.17
28 RRLKRRMDRY 0.18
29 RRRKRRMDRY 0.18
30 RRSKRIPRRY 0.18
31 RRSRRIMDRF 0.19
32 RRSRRIMDKY 0.19
33 RRRKRIPDRF 0.19
34 RRRKRIPDKY 0.19
35 RRRKRIPRRY 0.2
36 RRLKRIPDRF 0.2
37 RRSKRHPDRY 0.2
38 RRSRRIMRRY 0.2
39 RRLKRIPDKY 0.2
40 RRSKRRPDRY 0.21
41 RRRRRIMDKY 0.21
42 RRLKRIPRRY 0.21
43 RRRRRIMDRF 0.21
44 RRRRRIMRRY 0.22
45 RRLRRIMDKY 0.22
46 RRSRRHMDRY 0.22
47 RRRKRHPDRY 0.22
48 RRSKRIMDRH 0.22
49 RRLRRIMDRF 0.22
50 RRRKRRPDRY 0.23
51 RRLKRHPDRY 0.23
52 RRLRRIMRRY 0.23
53 RRSKRIMDKF 0.23
54 RRSRRRMDRY 0.23
55 RRRKRIMDRH 0.24
56 RRSKRIMRKY 0.24
57 RRRRRHMDRY 0.24
58 RRSRRIPDKY 0.24
59 RRLKRRPDRY 0.24
60 RRSKRIMRRF 0.24
61 RRLRRHMDRY 0.25
62 RRLKRIMDRH 0.25
63 RRSKRIMKRY 0.25
64 RRRKRIMDKF 0.25
65 RRSRRIPDRF 0.25
66 RRRRRRMDRY 0.25
67 RRRKRIMRRF 0.26
68 RRLRRRMDRY 0.26
69 RRSKRHMDRF 0.26
70 RRRKRIMRKY 0.26
71 RRLKRIMDKF 0.26
72 RRSKRHMDKY 0.26
73 RRSRRIPRRY 0.26
74 RRSKRRMDRF 0.27
75 RRRRRIPDRF 0.27
76 RRLKRIMRRF 0.27
77 RRSKRRMDKY 0.27
78 RRLKRIMRKY 0.27
79 RRSKRHMRRY 0.27
80 RRRRRIPDKY 0.27
81 RRLRRIPDKY 0.27
82 RRRKRIMKRY 0.28
83 RRSKRRMRRY 0.28
84 RRRRRIPRRY 0.28
85 RRRKRHMDRF 0.28
86 RRSRRHPDRY 0.28
87 RRSKRIPDKF 0.28
88 RRLKRIMKRY 0.28
89 RRLRRIPDRF 0.28
90 RRRKRHMDKY 0.28
  (binding_energy)(dif)  (stability_energy)(dif)

(data)

  

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# Precalculated Models Intraclash ΔGbinding Total
1 RRLKRIMDKY

1.34

-8.24

-6.9
2 RRLKRHMDRY

1.45

-8.25

-6.8
3 RRSKRIMDKY

1.66

-8.15

-6.49
4 RRRKRIMRRY

1.7

-8.08

-6.38
5 RRSKRHMDRY

1.41

-7.57

-6.16
6 RRLKRIPDRY

1.24

-7.3

-6.06
7 RRRKRIMDRY

1.7

-7.71

-6.01
8 RRRKRHMDRY

1.36

-7.32

-5.96
9 RRLKRIMDRF

1.41

-7.33

-5.92
10 RRLKRIMDRY

2.7

-8.49

-5.79
11 RRRKRIMDRF

1.77

-7.47

-5.7
12 RRRRRIPDRY

2.04

-7.64

-5.6
13 RRRRRIMDRY

2.5

-8.04

-5.54
14 RRSKRIPDKY

1.94

-7.29

-5.35
15 RRSKRIMDRF

2.01

-7.23

-5.22
16 RRLRRIPDRY

1.34

-6.55

-5.21
17 RRSKRIPDRF

1.4

-6.59

-5.19
18 RRLKRRMDRY

1.52

-6.68

-5.16
19 RRRKRIPDRY

1.31

-6.43

-5.12
20 RRSRRIPDRY

2.43

-7.54

-5.11
21 RRRKRRMDRY

1.69

-6.79

-5.1
22 RRSRRIMDRY

1.38

-6.36

-4.98
23 RRSKRRMDRY

1.93

-6.9

-4.97
24 RRSKRIMRRY

2.09

-6.96

-4.87
25 RRLRRIMDRY

1.5

-6.2

-4.7
26 RRSKRIPDRY

1.53

-6.2

-4.67
27 RRLKRIMRRY

2.14

-6.76

-4.62
28 RRRKRIMDKY

1.37

-5.9

-4.53
29 RRSKRIMDRY

2.54

-7.07

-4.53
30 RRSKRIPRRY

2.74

-7.03

-4.29

 NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

NOTE: No more than 10 sequences can be selected for new calculations.

If your favourite sequence is not included in this list, please visit the ADAN section Prediction from a query sequence.

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