ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-8.PDB
Scoring matrix: BUD14_1CKA-8_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.12
Foldx random average score for Saccharomyces cerevisiae: 12.167

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214021
Proteins after random average filtering: 7178
 Total fragments: 1267255
Proteins after disorder filtering: 4357
 Total fragments: 56730
Proteins after pattern filtering: 2128
 Total fragments: 11228
Proteins after MINT filtering: 12
 Total fragments: 109


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.12

-1.12

0.00

Best peptides

EFYYLFPR

0.00

-2.52

-1.40

         
Interactors      
P13186

APSYVPNR

9.36

-4.04

-2.92

EPLPEREP

9.51

-4.46

-3.34

PIPAALPP

9.68

-3.73

-2.61

Q12276

TRPKILPK

6.02

-4.96

-3.84

PPQQLPSR

8.05

-6.08

-4.96

PQRPLSGQ

8.69

-6.34

-5.22

P38853

PSPAPKDF

9.67

-2.99

-1.87

KPFDTPTI

10.90

-4.78

-3.66

SAPSPAPK

11.96

-1.98

-0.86

P40095

RIPVLPPP

7.72

-6.36

-5.24

PPPRSPNR

8.24

-6.12

-5.00

RSPNRPTL

8.76

-3.89

-2.77

P53858

LPEFEPNR

8.19

-4.40

-3.28

AYLPEFEP

8.87

-4.75

-3.63

EFEPNRPV

9.66

-4.44

-3.32

P42073

KRPPREPI

8.60

-2.17

-1.05

RPPREPIE

8.93

-5.32

-4.20

NKRPPREP

11.12

-4.78

-3.66

P40036

ELPPLSPK

8.54

-3.79

-2.67

SLPTTPGI

9.59

-4.76

-3.64

IELPPLSP

11.40

-3.68

-2.56

Q03016

ANPKILPK

6.62

-5.90

-4.78

PPQQLPSR

8.05

-6.08

-4.96

FSPANPKI

8.93

-3.62

-2.50

Q07807

PFPFAYPN

6.86

3.63

4.75

PIPVKMPK

7.90

-2.75

-1.63

MFMPPPPL

9.18

-4.78

-3.66

P40187

PSPPIYKK

5.77

4.18

5.30

EPLNLPNN

9.84

-6.28

-5.16

GNPSPPIY

10.44

-4.11

-2.99

P39960

NNPATPNQ

9.96

-4.38

-3.26

FDPTLPAS

9.98

-3.73

-2.61

FFDPTLPA

10.33

-0.15

0.97

P26570

PDPSTPSK

9.84

-4.39

-3.27

PSKPNLEV

10.40

-2.53

-1.41

STPSKPNL

10.55

-4.58

-3.46

 


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