ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-7.PDB
Scoring matrix: BUD14_1CKA-7_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 17.67
Foldx random average score for Saccharomyces cerevisiae: 13.962

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214021
Proteins after random average filtering: 7178
 Total fragments: 1386519
Proteins after disorder filtering: 4388
 Total fragments: 52096
Proteins after pattern filtering: 2053
 Total fragments: 10587
Proteins after MINT filtering: 12
 Total fragments: 94


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

17.67

-0.79

0.00

Best peptides

WRPIPYWW

0.00

-2.31

-1.52

         
Interactors      
P13186

PSYVPNRV

10.58

-3.23

-2.44

RPPIPAAL

11.16

-3.35

-2.56

APSYVPNR

11.63

-2.33

-1.54

Q12276

PSRKPKRG

8.34

-4.85

-4.06

PQQLPSRK

8.38

-5.41

-4.62

TRPKILPK

9.34

-2.81

-2.02

P38853

PTDTPTPR

12.53

-4.01

-3.22

PFDTPTIQ

12.79

-2.69

-1.90

PSPAPKDF

13.68

-2.83

-2.04

P40095

NNRIPVLP

10.70

-4.85

-4.06

PVLPPPRS

10.92

-4.27

-3.48

IPVLPPPR

11.51

-6.43

-5.64

P53858

LPEFEPNR

10.88

-4.05

-3.26

PRVKPDSQ

11.09

-4.46

-3.67

KPSPPSSK

11.74

-2.95

-2.16

P42073

PREPIEFD

10.97

-3.41

-2.62

KRPPREPI

11.32

-1.49

-0.70

PPREPIEF

11.87

-4.21

-3.42

P40036

LPTTPGIR

10.30

-5.67

-4.88

ELPPLSPK

11.98

-2.52

-1.73

LPPLSPKS

12.21

-3.05

-2.26

Q03016

PQQLPSRT

9.65

-4.91

-4.12

TNTKPSRP

10.03

-3.06

-2.27

ANPKILPK

10.77

-2.59

-1.80

Q07807

MMFMPPPP

9.04

-6.28

-5.49

PNPIPVKM

9.38

-4.32

-3.53

FMPPPPLS

9.80

-3.51

-2.72

P40187

PSPPIYKK

9.06

-2.92

-2.13

NPSPPIYK

11.51

-5.34

-4.55

PLNLPNNS

12.02

-3.80

-3.01

P39960

NPATPNQK

12.08

-4.03

-3.24

KFFDPTLP

12.29

-4.06

-3.27

P26570

TPSKPNLE

10.60

-3.56

-2.77

MEPKSPIL

11.12

-2.03

-1.24

EPKSPILK

11.13

-3.64

-2.85

 


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