ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-29.PDB
Scoring matrix: BUD14_1CKA-29_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.46
Foldx random average score for Saccharomyces cerevisiae: 13.082

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7177
 Total fragments: 1499468
Proteins after disorder filtering: 3963
 Total fragments: 42989
Proteins after pattern filtering: 1922
 Total fragments: 9990
Proteins after MINT filtering: 12
 Total fragments: 86


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.46

-0.95

0.00

Best peptides

DRKWWRKFRK

0.00

-5.85

-4.90

         
Interactors      
P13186

KAPSYVPNRV

8.23

-5.90

-4.95

SSIPMSPNYG

8.81

-7.47

-6.52

SIPMSPNYGN

10.94

-6.44

-5.49

Q12276

QLPSRKPKRG

6.43

-6.66

-5.71

PQRPLSGQNV

10.47

-5.89

-4.94

QQLPSRKPKR

10.68

-5.61

-4.66

P38853

NKPFDTPTIQ

11.61

-4.10

-3.15

DVPTDTPTPR

11.94

-4.26

-3.31

PFDTPTIQKE

12.13

-3.28

-2.33

P40095

RIPVLPPPRS

6.89

-8.31

-7.36

NRIPVLPPPR

7.89

-9.07

-8.12

LPPPRSPNRP

8.59

-6.02

-5.07

P53858

YLPEFEPNRP

8.08

-6.37

-5.42

DFLSTPRVKP

11.28

-7.01

-6.06

FLSTPRVKPD

11.63

-4.93

-3.98

P42073

NKRPPREPIE

10.26

-6.02

-5.07

KRPPREPIEF

10.61

-4.42

-3.47

PREPIEFDLN

10.77

-5.82

-4.87

P40036

SLPTTPGIRS

8.34

-7.44

-6.49

ELPPLSPKST

9.03

-6.42

-5.47

FKIELPPLSP

11.63

-6.80

-5.85

Q03016

NIPLLTPINS

9.10

-7.68

-6.73

QLPSRTPKKG

9.31

-5.59

-4.64

DNIPLLTPIN

10.79

-7.94

-6.99

Q07807

PMMFMPPPPL

8.85

-8.18

-7.23

PFPFAYPNPM

9.27

-7.94

-6.99

YIYYPTPNPI

9.88

-4.96

-4.01

P40187

DEPLNLPNNS

10.97

-6.26

-5.31

GNPSPPIYKK

11.34

-5.24

-4.29

EPLNLPNNSA

12.66

-6.54

-5.59

P39960

NIKFFDPTLP

9.62

-6.02

-5.07

NNPATPNQKM

11.31

-6.32

-5.37

IKFFDPTLPA

11.81

-6.54

-5.59

P26570

MEPKSPILKT

12.28

-6.14

-5.19

PSTPSKPNLE

12.29

-4.64

-3.69

EPKSPILKTN

12.79

-4.35

-3.40

 


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