ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-28.PDB
Scoring matrix: BUD14_1CKA-28_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.75
Foldx random average score for Saccharomyces cerevisiae: 15.864

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7178
 Total fragments: 1521087
Proteins after disorder filtering: 4441
 Total fragments: 71760
Proteins after pattern filtering: 2132
 Total fragments: 12021
Proteins after MINT filtering: 12
 Total fragments: 127


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.75

2.63

0.00

Best peptides

RKYMPPRKRM

0.00

-4.52

-7.15

         
Interactors      
P13186

SIPMSPNYGN

11.56

-3.42

-6.05

FKAPSYVPNR

12.09

-5.01

-7.64

PAALPPSDMT

12.30

-4.78

-7.41

Q12276

SPQRPLSGQN

10.91

-3.25

-5.88

DPPQQLPSRK

11.13

-4.29

-6.92

PQQLPSRKPK

11.44

-3.78

-6.41

P38853

KPFDTPTIQK

10.15

-1.72

-4.35

VPTDTPTPRN

11.29

-3.49

-6.12

TPVTPTSHQT

13.14

-4.11

-6.74

P40095

RIPVLPPPRS

10.41

-5.19

-7.82

VLPPPRSPNR

10.92

-4.92

-7.55

FPDSPSSSSL

12.99

-3.74

-6.37

P53858

EFEPNRPVSM

11.60

-1.49

-4.12

PKPSPPSSKL

11.61

-5.30

-7.93

DPKPSPPSSK

13.03

-0.85

-3.48

P42073

NKRPPREPIE

12.95

-3.04

-5.67

LNKRPPREPI

13.70

-4.33

-6.96

RPPREPIEFD

14.07

-2.28

-4.91

P40036

KIELPPLSPK

10.08

-5.27

-7.90

SKSLPTTPGI

10.37

-2.72

-5.35

IELPPLSPKS

13.43

-1.95

-4.58

Q03016

QQLPSRTPKK

10.83

-3.50

-6.13

KHPPISSPSN

11.90

-3.34

-5.97

PQQLPSRTPK

11.96

-2.97

-5.60

Q07807

FPFAYPNPMM

7.90

-5.44

-8.07

MMFMPPPPLS

10.33

-6.93

-9.56

YIYYPTPNPI

10.74

-5.71

-8.34

P40187

GNPSPPIYKK

13.04

-3.61

-6.24

MDEPLNLPNN

13.49

-4.45

-7.08

PLNLPNNSAH

13.83

-7.06

-9.69

P39960

NNPATPNQKM

12.48

-2.04

-4.67

DPTLPASNSS

12.77

-4.85

-7.48

LINNPATPNQ

13.25

-3.96

-6.59

P26570

NVPDPSTPSK

11.21

-3.37

-6.00

MEPKSPILKT

12.07

-4.24

-6.87

PKSPILKTNN

12.95

-2.09

-4.72

 


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