ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-26.PDB
Scoring matrix: BUD14_1CKA-26_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 12.29
Foldx random average score for Saccharomyces cerevisiae: 10.465

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1322735
Proteins after disorder filtering: 4516
 Total fragments: 83552
Proteins after pattern filtering: 2241
 Total fragments: 16782
Proteins after MINT filtering: 12
 Total fragments: 142


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

12.29

-1.14

0.00

Best peptides

RRPRPMHPH

0.00

-3.13

-1.99

         
Interactors      
P13186

FKAPSYVPN

6.26

-5.99

-4.85

LPEREPPTY

7.31

-4.78

-3.64

NSSIPMSPN

7.49

-4.64

-3.50

Q12276

SPQRPLSGQ

6.61

-5.36

-4.22

QLPSRKPKR

6.77

-4.27

-3.13

DPPQQLPSR

6.86

-6.47

-5.33

P38853

PYVPSESSQ

8.24

-4.16

-3.02

ATPVTPTSH

8.29

-2.45

-1.31

ASAPSPAPK

8.42

-4.02

-2.88

P40095

VLPPPRSPN

3.71

-4.71

-3.57

PPPRSPNRP

6.26

-5.78

-4.64

LPPPRSPNR

7.17

-5.56

-4.42

P53858

PKPSPPSSK

6.22

-2.90

-1.76

EPNRPVSMS

6.73

-4.44

-3.30

STPRVKPDS

7.05

-4.38

-3.24

P42073

RPPREPIEF

6.06

-5.05

-3.91

PREPIEFDL

6.41

-5.42

-4.28

KRPPREPIE

6.74

-5.75

-4.61

P40036

IELPPLSPK

6.32

-5.76

-4.62

SLPTTPGIR

7.39

-1.93

-0.79

KIELPPLSP

8.71

-4.54

-3.40

Q03016

KHPPISSPS

5.74

-3.99

-2.85

DPPQQLPSR

6.86

-6.47

-5.33

TDNIPLLTP

6.96

-7.31

-6.17

Q07807

MPPPPLSAP

3.76

-6.96

-5.82

SSPPNNSPF

6.44

-4.19

-3.05

IYYPTPNPI

7.14

-3.23

-2.09

P40187

DEPLNLPNN

7.54

-5.73

-4.59

NGNPSPPIY

7.92

-4.31

-3.17

MDEPLNLPN

8.04

-5.42

-4.28

P39960

NNPATPNQK

7.92

-3.35

-2.21

IKFFDPTLP

9.76

-3.17

-2.03

LINNPATPN

10.16

-1.55

-0.41

P26570

PSKPNLEVN

6.25

-4.63

-3.49

MEPKSPILK

6.36

-5.45

-4.31

PDPSTPSKP

7.04

-3.01

-1.87

 


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