ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-25.PDB
Scoring matrix: BUD14_1CKA-25_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.4
Foldx random average score for Saccharomyces cerevisiae: 15.605

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1434511
Proteins after disorder filtering: 4412
 Total fragments: 79095
Proteins after pattern filtering: 2260
 Total fragments: 16602
Proteins after MINT filtering: 12
 Total fragments: 144


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.40

4.32

0.00

Best peptides

RMRPFPRFF

0.00

-1.19

-5.51

         
Interactors      
P13186

DQQQAPLMP

10.66

-2.31

-6.63

SIPMSPNYG

11.60

-4.25

-8.57

RNSSIPMSP

12.80

-1.63

-5.95

Q12276

PPQQLPSRK

9.28

-2.42

-6.74

PQRPLSGQN

9.59

-2.60

-6.92

QLPSRKPKR

10.69

-2.15

-6.47

P38853

APSPAPKDF

11.35

-0.70

-5.02

KPFDTPTIQ

12.69

-1.70

-6.02

ATPVTPTSH

13.54

-0.63

-4.95

P40095

RIPVLPPPR

7.61

-5.52

-9.84

PPPRSPNRP

10.31

-1.86

-6.18

PVLPPPRSP

11.83

-3.79

-8.11

P53858

TPRVKPDSQ

10.99

-0.94

-5.26

LPEFEPNRP

11.07

-1.61

-5.93

FEPNRPVSM

11.15

-3.06

-7.38

P42073

LNKRPPREP

8.55

-3.88

-8.20

RPPREPIEF

8.65

-3.37

-7.69

KRPPREPIE

13.71

0.64

-3.68

P40036

SLPTTPGIR

9.71

-3.54

-7.86

ELPPLSPKS

9.86

-2.57

-6.89

KIELPPLSP

13.55

-2.51

-6.83

Q03016

KTNTKPSRP

10.15

-2.22

-6.54

SKPQTPILP

10.81

-4.98

-9.30

FSPANPKIL

11.69

-3.82

-8.14

Q07807

PMMFMPPPP

7.80

-5.61

-9.93

FPFAYPNPM

10.55

-3.05

-7.37

PFAYPNPMM

10.58

-0.75

-5.07

P40187

GNPSPPIYK

9.53

-2.49

-6.81

EPLNLPNNS

11.96

-2.96

-7.28

EENGNPSPP

13.43

-1.31

-5.63

P39960

NNPATPNQK

10.12

-2.19

-6.51

IKFFDPTLP

10.98

-0.70

-5.02

MLINNPATP

12.01

-3.31

-7.63

P26570

MEPKSPILK

10.97

-2.29

-6.61

DPTDSPNEW

11.62

-1.94

-6.26

STPSKPNLE

11.92

-2.06

-6.38

 


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