ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-21.PDB
Scoring matrix: BUD14_1CKA-21_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 14.86
Foldx random average score for Saccharomyces cerevisiae: 14.566

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7178
 Total fragments: 1943823
Proteins after disorder filtering: 4471
 Total fragments: 74684
Proteins after pattern filtering: 1792
 Total fragments: 4700
Proteins after MINT filtering: 13
 Total fragments: 45


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

14.86

-0.60

0.00

Best peptides

RWIFGIPTML

0.00

-0.29

0.31

         
Interactors      
P13186

PMSPNYGNQS

11.41

-1.90

-1.30

SSIPMSPNYG

11.89

-0.65

-0.05

PLTPLATNTH

11.96

-1.14

-0.54

Q12276

PQRPLSGQNV

11.65

-1.31

-0.71

QLPSRKPKRG

11.68

-1.28

-0.68

DPPQQLPSRK

13.36

-3.04

-2.44

P38853

NKPFDTPTIQ

5.27

-6.48

-5.88

PYVPSESSQT

10.45

-1.82

-1.22

APSPAPKDFS

11.15

-3.01

-2.41

P41818

PKTPYQGAVD

11.48

-2.42

-1.82

P40095

PRSPNRPTLS

7.87

-4.16

-3.56

P53858

EFEPNRPVSM

9.48

-3.30

-2.70

SMTPDSPVKS

10.79

-2.74

-2.14

STPRVKPDSQ

13.16

-2.19

-1.59

P42073

PREPIEFDLN

8.34

-3.67

-3.07

KRPPREPIEF

10.04

-2.68

-2.08

RPPREPIEFD

13.02

-3.89

-3.29

P40036

KSLPTTPGIR

9.74

-2.20

-1.60

ELPPLSPKST

10.79

-1.19

-0.59

PTTPGIRSGN

13.70

-0.12

0.48

Q03016

LFSPANPKIL

7.01

-2.85

-2.25

NIPLLTPINS

12.56

-3.01

-2.41

DPPQQLPSRT

13.07

-2.24

-1.64

Q07807

FRPSNNPAAV

14.56

-1.26

-0.66

P40187

NGNPSPPIYK

11.40

-1.66

-1.06

DEPLNLPNNS

14.38

-1.63

-1.03

P39960

INNPATPNQK

10.38

-2.12

-1.52

FFDPTLPASN

10.51

-1.69

-1.09

PATPNQKMRD

12.34

-3.18

-2.58

P26570

PKSPILKTNN

8.44

-2.27

-1.67

PSTPSKPNLE

11.49

-2.07

-1.47

STPLNSPGLS

13.41

-3.61

-3.01

 


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