ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-19.PDB
Scoring matrix: BUD14_1CKA-19_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.03
Foldx random average score for Saccharomyces cerevisiae: 14.133

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1434813
Proteins after disorder filtering: 4562
 Total fragments: 70160
Proteins after pattern filtering: 2170
 Total fragments: 9879
Proteins after MINT filtering: 13
 Total fragments: 94


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.03

-1.14

0.00

Best peptides

IRFFWGQCF

0.00

-6.02

-4.88

         
Interactors      
P13186

IPLTPLATN

10.06

-7.29

-6.16

SSIPMSPNY

11.39

-5.94

-4.81

PMSPNYGNQ

11.66

-5.71

-4.58

Q12276

ISTPTSTPT

12.19

-4.20

-3.07

KISTPTSTP

12.44

-5.53

-4.40

RRPSTTPSH

12.53

-4.10

-2.96

P38853

PVTPTSHQT

11.03

-3.63

-2.50

MDVPTDTPT

12.24

-6.26

-5.13

PFDTPTIQK

12.29

-5.77

-4.63

P41818

PKTPYQGAV

11.90

-5.50

-4.37

P40095

PRSPNRPTL

8.43

-9.12

-7.98

LPPPRSPNR

10.91

-8.05

-6.92

PDSPSSSSL

11.77

-5.76

-4.63

P53858

KPSPPSSKL

8.75

-9.01

-7.88

PNRPVSMSF

11.21

-6.46

-5.33

PRVKPDSQG

11.35

-4.76

-3.63

P42073

PREPIEFDL

10.32

-6.45

-5.32

NKRPPREPI

12.28

-9.95

-8.81

KRPPREPIE

13.66

-6.05

-4.92

P40036

LPTTPGIRS

9.60

-6.88

-5.75

PPLSPKSTV

11.79

-5.07

-3.94

KSLPTTPGI

11.95

-6.73

-5.60

Q03016

KPSRPSTSP

11.13

-5.62

-4.49

LFSPANPKI

11.83

-6.84

-5.71

DNIPLLTPI

12.34

-5.83

-4.70

Q07807

PFAYPNPMM

9.28

-7.32

-6.19

PVFRPSNNP

11.34

-6.71

-5.58

MPPPPLSAP

11.81

-8.98

-7.85

P40187

ENGNPSPPI

12.98

-6.39

-5.25

MDEPLNLPN

13.13

-5.70

-4.57

NPSPPIYKK

13.45

-8.39

-7.26

P39960

NPATPNQKM

9.80

-8.50

-7.37

PATPNQKMR

11.14

-6.16

-5.03

DPTLPASNS

14.09

-6.80

-5.67

P26570

PKSPILKTN

11.91

-4.34

-3.21

PLNSPGLSK

11.92

-4.26

-3.13

PSTPSKPNL

12.15

-5.54

-4.41

 


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