ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-17.PDB
Scoring matrix: BUD14_1CKA-17_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.5
Foldx random average score for Saccharomyces cerevisiae: 16.253

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1379151
Proteins after disorder filtering: 4452
 Total fragments: 57533
Proteins after pattern filtering: 1965
 Total fragments: 6661
Proteins after MINT filtering: 13
 Total fragments: 64


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.50

-1.80

0.00

Best peptides

MRFMWGYWF

0.00

-7.71

-5.91

         
Interactors      
P13186

SSIPMSPNY

12.57

-6.64

-4.84

IPMSPNYGN

14.25

-4.35

-2.55

PMSPNYGNQ

15.45

-7.03

-5.23

Q12276

RRPSTTPSH

10.88

-5.28

-3.48

QLPSRKPKR

13.67

-5.73

-3.93

DPPQQLPSR

15.01

-4.80

-3.00

P38853

NKPFDTPTI

15.42

-6.93

-5.13

PFDTPTIQK

15.72

-1.84

-0.04

PTDTPTPRN

15.84

-3.79

-1.99

P41818

PKTPYQGAV

16.05

-7.06

-5.26

P40095

LPPPRSPNR

10.17

-7.52

-5.72

PRSPNRPTL

11.35

-6.34

-4.54

FPDSPSSSS

15.32

-3.12

-1.32

P53858

YLPEFEPNR

10.72

-5.43

-3.63

PNRPVSMSF

13.61

-4.98

-3.18

PRVKPDSQG

13.79

-3.58

-1.78

P42073

NKRPPREPI

13.66

-8.39

-6.59

PREPIEFDL

13.73

-4.57

-2.77

PPREPIEFD

16.15

-6.05

-4.25

P40036

LPTTPGIRS

12.48

-5.27

-3.47

KSLPTTPGI

14.82

-5.39

-3.59

IELPPLSPK

15.90

-5.86

-4.06

Q03016

LFSPANPKI

14.45

-8.24

-6.44

QLPSRTPKK

14.79

-4.99

-3.19

DPPQQLPSR

15.01

-4.80

-3.00

Q07807

FRPSNNPAA

13.18

-5.20

-3.40

NTPVFRPSN

13.61

-4.22

-2.42

YIYYPTPNP

14.17

-8.55

-6.75

P40187

NPSPPIYKK

13.49

-7.11

-5.31

ENGNPSPPI

14.36

-5.35

-3.55

DEPLNLPNN

15.78

-5.53

-3.73

P39960

INNPATPNQ

14.02

-6.07

-4.27

NPATPNQKM

14.23

-5.43

-3.63

PATPNQKMR

15.76

-5.13

-3.33

P26570

PLNSPGLSK

13.88

-3.54

-1.74

EPKSPILKT

15.61

-4.93

-3.13

STPLNSPGL

15.78

-6.98

-5.18

 


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