ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKA-15.PDB
Scoring matrix: BUD14_1CKA-15_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.61
Foldx random average score for Saccharomyces cerevisiae: 14.251

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1515014
Proteins after disorder filtering: 4093
 Total fragments: 40033
Proteins after pattern filtering: 1728
 Total fragments: 5429
Proteins after MINT filtering: 12
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.61

1.55

0.00

Best peptides

MIWLWYKRR

0.00

-4.41

-5.96

         
Interactors      
P13186

KAPSYVPNR

10.05

-1.40

-2.95

IPLTPLATN

11.83

-2.75

-4.30

PMSPNYGNQ

12.40

-1.78

-3.33

Q12276

DPPQQLPSR

10.55

-3.44

-4.99

LPSRKPKRG

11.39

-3.93

-5.48

QLPSRKPKR

11.66

-4.18

-5.73

P38853

NKPFDTPTI

11.19

-2.18

-3.73

KPFDTPTIQ

11.92

-0.44

-1.99

VPTDTPTPR

13.72

-2.40

-3.95

P40095

RIPVLPPPR

10.26

-4.84

-6.39

LPPPRSPNR

10.64

-2.70

-4.25

IPVLPPPRS

12.37

-4.74

-6.29

P53858

YLPEFEPNR

8.98

-2.74

-4.29

KPSPPSSKL

12.19

-2.89

-4.44

LPEFEPNRP

12.57

-4.11

-5.66

P42073

PREPIEFDL

13.47

-1.16

-2.71

KRPPREPIE

13.62

-1.41

-2.96

RPPREPIEF

13.80

-1.80

-3.35

P40036

SLPTTPGIR

10.32

-2.33

-3.88

LPPLSPKST

12.94

-3.32

-4.87

KIELPPLSP

13.04

-3.54

-5.09

Q03016

NIPLLTPIN

10.16

-3.91

-5.46

DPPQQLPSR

10.55

-3.44

-4.99

LFSPANPKI

11.59

-2.72

-4.27

Q07807

MMFMPPPPL

10.53

-5.40

-6.95

PFPFAYPNP

11.68

-3.34

-4.89

PFAYPNPMM

11.69

-3.97

-5.52

P40187

NPSPPIYKK

11.70

-3.95

-5.50

DEPLNLPNN

12.44

-2.15

-3.70

P39960

NPATPNQKM

11.93

-2.78

-4.33

PATPNQKMR

12.57

-2.19

-3.74

P26570

MEPKSPILK

10.49

-1.92

-3.47

STPLNSPGL

12.73

-2.63

-4.18

TPSKPNLEV

13.16

-1.72

-3.27

 


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