ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-23.PDB
Scoring matrix: ABP1_1JO8-23_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.26
Foldx random average score for Saccharomyces cerevisiae: 13.025

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186332
Proteins after random average filtering: 5078
 Total fragments: 1135080
Proteins after disorder filtering: 3399
 Total fragments: 76187
Proteins after pattern filtering: 1495
 Total fragments: 6556
Proteins after MINT filtering: 27
 Total fragments: 180


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.26

-0.33

0.00

Best peptides

RPLGRYP

0.00

-5.99

-5.66

         
Interactors      
P09119

QVPLTPT

10.02

-1.87

-1.54

P43603

APTSPST

12.81

-0.99

-0.66

P53145

PLPGQPP

7.27

-2.17

-1.84

EPLLPPL

7.64

-3.79

-3.46

LPPLPGQ

8.96

-1.97

-1.64

P48562

FPRGPMH

5.26

-5.46

-5.13

RGPMHPN

6.65

-4.25

-3.92

APRAPYP

7.75

-3.68

-3.35

P17555

RPKKPST

4.95

-4.87

-4.54

PPPRPKK

8.85

-1.98

-1.65

PRPKKPS

10.32

-0.86

-0.53

P40494

RPPRPPP

4.63

-4.86

-4.53

KPTLIPD

8.89

-1.69

-1.36

PNMMPVT

10.26

-1.32

-0.99

P08458

LPKRKPP

6.32

-4.21

-3.88

PKRKPPK

8.06

-4.23

-3.90

NLPKRKP

9.07

-1.78

-1.45

P40325

RPPRPAA

6.31

-3.90

-3.57

RPHQRPS

7.67

-3.33

-3.00

RPQQNPS

7.79

-2.06

-1.73

P40095

IPVLPPP

7.82

-3.89

-3.56

RSPNRPT

9.65

-1.57

-1.24

PPPRSPN

9.78

-1.71

-1.38

Q12168

PPPLPPR

8.55

-3.90

-3.57

VPNRPGG

10.93

-1.24

-0.91

PVPKPNI

11.09

-1.31

-0.98

Q06449

PSNLPPP

9.32

-2.08

-1.75

QPQQAPP

9.56

-0.82

-0.49

QPQQQPQ

10.86

-1.47

-1.14

P32793

GPTHPSN

12.35

0.39

0.72

P32790

PPIKPPR

8.22

-4.74

-4.41

KPPRPTS

8.45

-2.74

-2.41

MPARPTA

9.14

-1.43

-1.10

Q01389

RYPQTPS

8.77

-2.15

-1.82

FPNLTPN

9.29

-1.38

-1.05

TPSRPVP

9.61

-1.65

-1.32

P53974

LKPKPPP

7.93

-2.16

-1.83

PPPKPLL

9.83

-1.32

-0.99

PPPKPSH

10.56

-1.17

-0.84

Q06836

RGPLLPD

7.04

-3.16

-2.83

KPPLSPS

7.96

-3.95

-3.62

GPLLPDD

9.36

-3.40

-3.07

Q05580

LPQLPPP

6.71

-4.32

-3.99

PPPKPKV

10.56

-0.80

-0.47

NLPQLPP

10.90

-1.32

-0.99

P53933

SYPGNPT

8.85

-1.47

-1.14

PPPLPNR

9.04

-4.61

-4.28

DLPMELP

10.52

-0.42

-0.09

Q04439

KPKEPMF

7.67

-2.56

-2.23

KKPAPPP

8.14

-3.55

-3.22

PPPSSKP

11.01

-2.42

-2.09

Q08873

PVLGPQL

7.00

-3.35

-3.02

KKPRPPV

8.57

-1.28

-0.95

FPVLGPQ

9.35

-3.32

-2.99

P38885

APPSPEN

12.45

-1.51

-1.18

P50942

HPLKPCD

7.34

-2.43

-2.10

IVPRPCP

8.80

-1.16

-0.83

KPEKPPV

9.69

-1.53

-1.20

P48415

PRSGPIN

7.66

-2.07

-1.74

SPTGPNP

7.69

-1.97

-1.64

QPVGPVA

8.23

-2.55

-2.22

P40563

QPQGPSD

7.31

-1.87

-1.54

VNPGQLP

7.67

-2.73

-2.40

TPAGTPN

8.52

-1.38

-1.05

P38822

PAPEVPP

12.06

-0.58

-0.25

Q12134

PVPSPMN

12.08

-1.40

-1.07

P39743

SNPLTSP

10.00

-0.86

-0.53

TIPEDNP

12.77

0.24

0.57

 


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