ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-19.PDB
Scoring matrix: ABP1_1JO8-19_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.35
Foldx random average score for Saccharomyces cerevisiae: 16.392

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176176
Proteins after random average filtering: 5078
 Total fragments: 980952
Proteins after disorder filtering: 3153
 Total fragments: 61618
Proteins after pattern filtering: 1502
 Total fragments: 7411
Proteins after MINT filtering: 26
 Total fragments: 213


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.35

0.30

0.00

Best peptides

KISRPGRSF

0.00

-8.40

-8.70

         
Interactors      
P09119

LTPTTSPVK

15.43

-0.66

-0.96

PTTSPVKKS

15.72

-4.10

-4.40

PLTPTTSPV

15.86

-3.08

-3.38

P40325

QSQPPRPPR

12.14

-6.04

-6.34

RPPRPAANL

12.44

-10.69

-10.99

LYVQPGDPR

12.56

-3.05

-3.35

P53145

PGQPPLINI

11.17

-4.62

-4.92

PLLPPLPGQ

13.68

-5.11

-5.41

P48562

NPYRPHHNM

9.51

-7.96

-8.26

QPQSPLSSQ

10.35

-3.97

-4.27

PISAPRAPY

11.14

-5.47

-5.77

P17555

PPAPPASVF

10.70

-4.74

-5.04

RPKKPSTLK

11.54

-8.00

-8.30

PPRPKKPST

11.80

-4.73

-5.03

P40494

PRPPPKPLH

12.54

-6.51

-6.81

PNMMPVTHV

14.46

-4.95

-5.25

QPPNMMPVT

15.82

-2.20

-2.50

P08458

PITNPSSSS

11.65

-3.44

-3.74

NLPKRKPPK

14.65

-7.43

-7.73

MTNLPKRKP

15.93

-7.69

-7.99

P43603

APTSPSTSS

12.40

-4.30

-4.60

FTAPTSPST

13.78

-1.36

-1.66

RFTAPTSPS

15.38

-3.21

-3.51

P40095

LPPPRSPNR

10.06

-5.47

-5.77

FPDSPSSSS

11.98

-3.95

-4.25

PPRSPNRPT

12.93

-4.04

-4.34

Q12168

PPLPPRANV

11.19

-6.51

-6.81

VPNRPGGTT

11.55

-7.69

-7.99

RGPPPLPPR

12.31

-6.40

-6.70

Q06449

PFPPPSTNY

11.31

-4.61

-4.91

P32793

GHGPTHPSN

13.55

-1.59

-1.89

PTHPSNMSN

14.50

-0.95

-1.25

GPTHPSNMS

16.34

-3.08

-3.38

P32790

PPAMPARPT

12.08

-4.42

-4.72

PIKPPRPTS

12.33

-5.62

-5.92

APAPLDPFK

12.64

-2.45

-2.75

Q01389

RPVPPDSSY

8.00

-5.41

-5.71

YPQTPSYYY

9.62

-4.23

-4.53

RRYPQTPSY

11.63

-5.60

-5.90

P53974

PTPPPKPSH

11.36

-3.66

-3.96

LINPPDPHS

11.62

-5.26

-5.56

PPPKPSHLK

11.77

-5.53

-5.83

Q06836

PPLSPSSFI

11.33

-4.08

-4.38

KNKPPLSPS

13.74

-3.69

-3.99

PLLPDDANI

14.22

-4.76

-5.06

Q05580

QLPPPKPKV

10.56

-7.09

-7.39

PPPKPKVQI

11.90

-6.03

-6.33

P53933

VAPPPLPNR

11.19

-4.53

-4.83

PPPPPIPST

13.85

-4.85

-5.15

PPPLPNRQL

15.87

-7.87

-8.17

Q04439

APPPPGMQN

10.22

-4.20

-4.50

PPPPGMQNK

13.02

-5.05

-5.35

RPSPPTAAT

13.27

-4.31

-4.61

Q08873

KPRPPVKSK

9.26

-6.21

-6.51

PVLGPQLST

13.11

-2.67

-2.97

STKKPRPPV

15.69

-4.00

-4.30

P38885

APPSPENSH

11.58

-4.68

-4.98

PPSPENSHQ

12.86

-4.36

-4.66

P50942

RPCPPIRRK

9.33

-6.47

-6.77

PPPPTSRHN

10.58

-4.25

-4.55

PCPPIRRKS

11.79

-4.08

-4.38

P48415

PPPPPIVKR

11.91

-5.92

-6.22

PSSPISRIS

12.28

-1.30

-1.60

PVSPYGQAT

12.76

-2.06

-2.36

P40563

PSERPKRRA

12.51

-4.60

-4.90

RAPPPVPKK

13.38

-5.29

-5.59

AGTPNVPTR

13.98

-3.79

-4.09

Q12134

PVPSPMNSQ

12.86

-3.33

-3.63

P39743

AYSNPLTSP

14.92

-3.83

-4.13

 


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