ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1JO8-13.PDB
Scoring matrix: ABP1_1JO8-13_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.43
Foldx random average score for Saccharomyces cerevisiae: 12.894

Available information for P15891 in MINT (Nov 2008):
Nš of interacting proteins: 39
 Proteins belonging to other specie: 0
Nš of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181254
Proteins after random average filtering: 5078
 Total fragments: 957597
Proteins after disorder filtering: 3060
 Total fragments: 46203
Proteins after pattern filtering: 1481
 Total fragments: 8432
Proteins after MINT filtering: 27
 Total fragments: 289


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.43

-0.94

0.00

Best peptides

RRRRHPFR

0.00

-9.38

-8.44

         
Interactors      
P09119

PTTSPVKK

10.35

-5.24

-4.30

TPTTSPVK

10.93

-3.44

-2.50

MSAIPITP

10.98

-4.55

-3.61

P43603

RFTAPTSP

10.72

-4.18

-3.24

P53145

LPGQPPLI

9.23

-6.26

-5.32

LPPLPGQP

9.35

-7.42

-6.48

EPLLPPLP

10.93

-5.35

-4.41

P48562

MRQAPKRP

7.08

-6.87

-5.93

GVAKPKKP

8.95

-6.94

-6.00

SPLNPYRP

9.26

-6.94

-6.00

P17555

GPPPRPKK

7.38

-6.33

-5.39

RPKKPSTL

8.10

-7.99

-7.05

PPPRPKKP

8.23

-7.54

-6.60

P40494

RPPRPPPK

5.57

-8.25

-7.31

RPPPKPLH

7.01

-7.45

-6.51

DKSRPPRP

7.16

-7.27

-6.33

P08458

LPKRKPPK

6.92

-6.64

-5.70

PKRKPPKL

7.60

-6.78

-5.84

NLPKRKPP

10.01

-3.15

-2.21

P40325

QPPRPPRP

6.24

-9.13

-8.19

RPPPRPQQ

7.15

-7.94

-7.00

RPPRPAAN

7.95

-9.43

-8.49

P40095

RIPVLPPP

9.13

-5.25

-4.31

IPVLPPPR

9.14

-6.43

-5.49

RSPNRPTL

9.91

-4.75

-3.81

Q12168

DPYFPQFR

8.56

-5.47

-4.53

NRGPPPLP

9.09

-4.93

-3.99

PPPVPNRP

9.19

-7.96

-7.02

Q06449

NLPPPPQY

10.32

-5.23

-4.29

QPQQQPQQ

11.57

-4.24

-3.30

GPSNLPPP

11.67

-2.38

-1.44

P32793

GPTHPSNM

12.57

-5.07

-4.13

P32790

LPPIKPPR

6.91

-6.70

-5.76

PPIKPPRP

7.91

-6.86

-5.92

PPAMPARP

8.67

-7.95

-7.01

Q01389

YPQTPSYY

7.47

-6.41

-5.47

KRSKPLPP

7.72

-5.10

-4.16

EPSTPSRP

9.22

-6.77

-5.83

P53974

LKPKPPPK

6.70

-6.40

-5.46

KPKPPPKP

7.13

-6.97

-6.03

KPTPPPKP

7.43

-6.61

-5.67

Q06836

NKPPLSPS

11.48

0.04

0.98

KNKPPLSP

11.97

-3.44

-2.50

KPPLSPSS

12.22

-3.18

-2.24

Q05580

LPPPKPKV

7.98

-6.51

-5.57

LPQLPPPK

9.25

-6.09

-5.15

PPPKPKVQ

10.34

-5.92

-4.98

P53933

RPPPPPIP

6.62

-7.30

-6.36

RRRPPPPP

7.86

-6.60

-5.66

RVAPPPLP

8.07

-6.36

-5.42

Q04439

KPKEPMFE

8.51

-4.47

-3.53

KKPAPPPP

9.17

-3.88

-2.94

NIPTPPQN

9.76

-5.07

-4.13

Q08873

KKPRPPVK

4.59

-7.08

-6.14

KPRPPVKS

7.93

-6.06

-5.12

TKKPRPPV

11.15

-2.62

-1.68

P38885

APPSPENS

12.86

-3.15

-2.21

P50942

RPCPPIRR

5.38

-10.45

-9.51

PRPCPPIR

7.29

-6.76

-5.82

KPEKPPVV

7.67

-6.66

-5.72

P48415

GPKTKPRS

8.22

-7.09

-6.15

RPPVIPLG

9.77

-3.44

-2.50

SPKPPVVK

9.91

-5.42

-4.48

P40563

RRAPPPVP

7.16

-7.39

-6.45

PSERPKRR

8.67

-6.78

-5.84

TPKVPERP

9.13

-7.00

-6.06

P38822

PEVPPPRR

8.69

-7.94

-7.00

APEVPPPR

9.81

-5.62

-4.68

RGPAPEVP

12.24

-4.93

-3.99

Q12134

QPVPSPMN

11.80

-3.95

-3.01

P39743

NPLTSPVA

11.92

-2.60

-1.66

YSNPLTSP

12.76

-1.79

-0.85

 


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