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Matrix information:
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ADAN-name: 2B052.PDB
Scoring matrix: 2B052_mat
Uniprot code: P61981
Genome source: Homo sapiens
Wild-type ligand: RAIsLP
Foldx wt ligand score: 1.83
Foldx random average score for Homo sapiens: 10.129 Available information for P61981 in MINT (Nov 2008):
Nš of interacting proteins: 204
Proteins belonging to other specie: 1
Nš of interactions described: 229
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18372033
Proteins after random average filtering: 40313
Total fragments: 10097773
Proteins after disorder filtering: 31973
Total fragments: 1115971
Proteins after pattern filtering: 3280
Total fragments: 4125
Proteins after MINT filtering: 21
Total fragments: 29
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RAIsLP |
1.83
|
-15.22 |
0.00 |
| Best peptides |
FPWEYW |
0.00
|
-10.89 |
4.33 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q86X29 |
RSSSAG |
8.22
|
-5.97 |
9.25 |
| Q96TC7 |
RSQSLP |
5.62
|
-10.92 |
4.30 |
| Q13009 |
RSSSTP |
7.34
|
-9.15 |
6.07 |
| Q9NYF8 |
RGDSKG |
7.18
|
-7.62 |
7.60 |
|
RDESRG |
7.46
|
-9.02 |
6.20 |
| Q8N3F8 |
RGSSGP |
7.76
|
-6.44 |
8.78 |
|
RSGTRP |
9.30
|
-7.41 |
7.81 |
| P10398 |
RGGSDG |
9.12
|
-6.52 |
8.70 |
| Q6W9G7 |
RTRSEP |
6.69
|
-10.33 |
4.89 |
|
RAQSSP |
7.11
|
-8.79 |
6.43 |
| P49815 |
RSMSGG |
7.23
|
-8.52 |
6.70 |
| P49761 |
RSPSFG |
8.64
|
-8.48 |
6.74 |
| O75494 |
RSWTSP |
8.34
|
-6.58 |
8.64 |
| Q9Y2U5 |
RAQSYP |
4.38
|
-9.56 |
5.66 |
|
RDRSSP |
7.74
|
-7.88 |
7.34 |
| O96013 |
RPLSGP |
6.33
|
-9.48 |
5.74 |
|
REGSGG |
8.75
|
-5.36 |
9.86 |
| P16471 |
RPGTDG |
10.07
|
-6.87 |
8.35 |
| Q9UDY2 |
RLNSHG |
7.41
|
-8.04 |
7.18 |
| O75044 |
RPSSQP |
7.09
|
-11.27 |
3.95 |
|
RSDSHG |
7.70
|
-7.65 |
7.57 |
| Q8IUD2 |
RTNSTG |
7.62
|
-9.10 |
6.12 |
| P15056 |
RSSSAP |
7.84
|
-6.69 |
8.53 |
| Q15287 |
RSKSKP |
6.08
|
-10.13 |
5.09 |
|
RSASSG |
8.23
|
-6.93 |
8.29 |
| Q96SB4 |
RPLTRP |
7.45
|
-11.46 |
3.76 |
| Q99459 |
RTPSNG |
9.26
|
-8.21 |
7.01 |
|
RSGTTP |
9.29
|
-7.40 |
7.82 |
| Q6ZU52 |
RSPSAP |
9.32
|
-6.37 |
8.85 |
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