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Matrix information:
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ADAN-name: 1YWT2.PDB
Scoring matrix: 1YWT2_mat
Uniprot code: P31947
Genome source: Homo sapiens
Wild-type ligand: SHsYPA
Foldx wt ligand score: 1.78
Foldx random average score for Homo sapiens: 12.163 Available information for P31947 in MINT (Nov 2008):
Nš of interacting proteins: 130
Proteins belonging to other specie: 1
Nš of interactions described: 145
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 2573
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 45488
Total fragments: 21210340
Proteins after random average filtering: 45482
Total fragments: 10927036
Proteins after disorder filtering: 35863
Total fragments: 1391589
Proteins after pattern filtering: 1950
Total fragments: 2168
Proteins after MINT filtering: 13
Total fragments: 15
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
SHsYPA |
1.78
|
-15.85 |
0.00 |
| Best peptides |
SNsFGs |
0.00
|
-10.58 |
5.27 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q8TF72 |
RHLTPP |
9.85
|
-6.92 |
8.93 |
| Q96PE2 |
RLSSGG |
10.04
|
-7.07 |
8.78 |
| O96013 |
RRDSPP |
8.63
|
-9.27 |
6.58 |
|
REGSGG |
10.87
|
-4.80 |
11.05 |
| O43166 |
RNASKG |
11.07
|
-7.28 |
8.57 |
| Q96IF1 |
RGATGG |
10.82
|
-5.44 |
10.41 |
| O75592 |
RAESPG |
8.71
|
-9.94 |
5.91 |
| P49815 |
RSMSGG |
11.30
|
-5.15 |
10.70 |
| Q8TEW8 |
RSPSPP |
11.20
|
-7.15 |
8.70 |
| Q2M3G4 |
RTQSPG |
10.32
|
-7.87 |
7.98 |
| Q5T5U3 |
RTTSPP |
11.61
|
-6.53 |
9.32 |
| O94885 |
RGLSPP |
12.12
|
-7.08 |
8.77 |
| Q9UQ35 |
RSATPP |
10.72
|
-6.58 |
9.27 |
|
RSSTGP |
11.23
|
-5.22 |
10.63 |
| Q6ZU52 |
RNETPP |
6.88
|
-11.27 |
4.58 |
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