ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1X8S2.PDB
Scoring matrix: 1X8S2_mat
Uniprot code: O97111
Genome source: Drosophila melanogaster
Wild-type ligand: HREMAVDCP
Foldx wt ligand score: 5.6
Foldx random average score for Drosophila melanogaster: 13.817

Available information for O97111 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 1
Nš of interactions described: 19
 Interactions with other species: 3

Genome scanning information:
Subcellular location: True
Proteins in genome Drosophila melanogaster: 30509
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 4389
Total scanned proteins: 26119
 Total fragments: 13330536
Proteins after random average filtering: 26119
 Total fragments: 8345834
Proteins after disorder filtering: 19492
 Total fragments: 661220
Proteins after pattern filtering: 11855
 Total fragments: 43074
Proteins after MINT filtering: 5
 Total fragments: 34


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

HREMAVDCP

5.60

-18.20

0.00

Best peptides

EFMMAIDVM

0.00

-18.01

0.19

         
Interactors      
Q9VB22

ASAENVSSL

10.59

-10.29

7.91

AENVSSLGL

12.69

-8.23

9.97

GQTGRGATV

12.72

-5.93

12.27

Q8WRS3

NNNSHIVGI

9.20

-12.70

5.50

PKRNLGMVV

9.37

-11.35

6.85

TVPDDLSLA

9.58

-11.06

7.14

O96782

ANPSQNLAV

11.28

-10.06

8.14

AAPAPPIPV

11.33

-11.39

6.81

GKTCSNLNA

11.71

-9.54

8.66

P16371

MGALNPFGA

9.64

-11.10

7.10

LNPFGALGA

11.14

-9.34

8.86

GALGATMGL

11.62

-10.48

7.72

Q9VCU7

PTPGPAISA

11.94

-9.58

8.62

 


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